Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

324
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
324
Aging01:26

Aging

206
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
206
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

270
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
270
Neuroplasticity01:01

Neuroplasticity

843
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
843
Higher Mental Functions of Brain: Learning and Memory01:26

Higher Mental Functions of Brain: Learning and Memory

980
Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or...
980
Long-term Potentiation01:35

Long-term Potentiation

55.9K
Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
55.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effectiveness and safety of repeat dose subcutaneous ketamine for treatment-resistant depression, and the impact of prior ketamine treatment: open label extension of the KADS study.

The British journal of psychiatry : the journal of mental science·2026
Same author

Towards an Integrated Staging Model for Bipolar Disorders: An International Society for Bipolar Disorders (ISBD) Staging Task Force Consensus Report.

Bipolar disorders·2026
Same author

Geographic Variation in Loneliness and Social Isolation in Australia: Socio-Demographic and Healthcare Utilisation Determinants.

Healthcare (Basel, Switzerland)·2026
Same author

Guidelines for the prevention of psychosis from the World Federation of Societies of Biological Psychiatry (WFSBP) and EPI Canada.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry·2026
Same author

Associations of gait speed, grip strength, depressive symptoms, and their combinations with fracture risk in older adults.

GeroScience·2026
Same author

Tell me lies, tell me sweet little lies: power calculations in clinical trials.

The British journal of psychiatry : the journal of mental science·2026

Related Experiment Video

Updated: Sep 22, 2025

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
12:28

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

17.6K

Investing in Late-Life Brain Capital.

Walter D Dawson1, Erin Smith2, Laura Booi2

  • 1Department of Neurology, School of Medicine, Oregon Health & Science University, Portland, Oregon, USA.

Innovation in Aging
|May 23, 2022
PubMed
Summary

Older adults are undervalued, impacting their well-being. Optimizing late-life Brain Capital through investment and initiatives can enhance health and societal contributions.

Keywords:
AgingBrain healthInnovationMental disordersNeurosciencePsychiatry

More Related Videos

Brain Banking: Making the Most of your Research Specimens
08:12

Brain Banking: Making the Most of your Research Specimens

Published on: July 24, 2009

10.1K
Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

45.8K

Related Experiment Videos

Last Updated: Sep 22, 2025

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
12:28

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

17.6K
Brain Banking: Making the Most of your Research Specimens
08:12

Brain Banking: Making the Most of your Research Specimens

Published on: July 24, 2009

10.1K
Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

45.8K

Area of Science:

  • Gerontology
  • Neuroscience
  • Public Health

Background:

  • Older adults often face societal undervaluation and underappreciation.
  • This marginalization exacerbates challenges and overlooks the value of late life.
  • Positive aspects of aging are crucial for individual and societal well-being.

Purpose of the Study:

  • To propose a novel approach for enhancing health and well-being in older adults.
  • To introduce the concept of optimizing late-life Brain Capital.
  • To advocate for investment and initiatives in late-life Brain Capital.

Main Methods:

  • Conceptual framework development.
  • Literature review on aging, brain health, and societal value.
  • Proposal for strategic investment and initiative design.

Main Results:

  • Identified undervaluation as a significant barrier for older adults.
  • Conceptualized 'late-life Brain Capital' as a valuable asset.
  • Outlined a framework for optimizing this capital.

Conclusions:

  • Prioritizing late-life Brain Capital is essential for 21st-century demands.
  • Investing in and developing initiatives for late-life Brain Capital can elevate well-being.
  • Recognizing and optimizing the contributions of older adults benefits society.