Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Disorders01:29

Bone Disorders

4.0K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
4.0K
Bone Markings01:26

Bone Markings

6.5K
Bones have various surface features that help form joints and attach to other soft tissues. Depending on the function, bone markings are categorized into articulating projections, processes for attachment, depressions, and openings.
Articulating Projections
Articulating projections are found where two bones meet to form a joint. These structures are usually found at the ends of bones. The largest articulation is a rounded projection called the head, supported by a narrow neck at the ends of...
6.5K
Blood and Nerve Supply to the Bones01:29

Blood and Nerve Supply to the Bones

12.0K
Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
12.0K
Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

7.9K
Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
7.9K
Compact Bone01:27

Compact Bone

13.1K
Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
13.1K
Bones of the Lower Limb: Tibia and Fibula01:10

Bones of the Lower Limb: Tibia and Fibula

5.5K
The tibia is the main weight-bearing bone of the lower leg. It is larger than the fibula with which it is paired. The tibia is also the second longest bone in the body and is located right below the skin. The proximal end of the tibia forms the medial and the lateral condyle, which articulates with the condyles of the femur to form the knee joint. Between the articulating surfaces is the irregular elevated area known as the intercondylar eminence that serves as the inferior attachment point for...
5.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Classification of spinal tuberculous infection, pyogenic infection and spinal metastasis from magnetic resonance imaging using machine learning.

BMC musculoskeletal disorders·2026
Same author

Technical Errors and Artifacts Causing Mistakes in Musculoskeletal Imaging.

Seminars in musculoskeletal radiology·2025
Same author

Short- and Long-Term Efficacy of Hyperbaric Oxygen Therapy in Irradiated Breast Cancer Patients With Long-Standing Lymphedema: A Prospective Case Series.

Cancer reports (Hoboken, N.J.)·2025
Same author

Imaging of thoracic tuberculosis: pulmonary and extrapulmonary.

BJR open·2024
Same author

Imaging of supra-thoracic tuberculosis.

Journal of medical imaging and radiation oncology·2024
Same author

Can conventional magnetic resonance imaging at presentation predict chemoresistance in osteosarcoma?

The British journal of radiology·2024

Related Experiment Video

Updated: Sep 22, 2025

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
08:57

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

2.1K

Benign incidental do-not-touch bone lesions.

Nuttaya Pattamapaspong1, Wilfred Cg Peh2

  • 1Department of Radiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

The British Journal of Radiology
|May 23, 2022
PubMed
Summary

Radiologists can misdiagnose benign bone lesions as malignant, leading to unnecessary treatments. This review helps identify these "do-not-touch" bone incidentalomas, distinguishing them from dangerous pathologies.

More Related Videos

A Simple Critical-sized Femoral Defect Model in Mice
09:41

A Simple Critical-sized Femoral Defect Model in Mice

Published on: March 15, 2015

15.3K
Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
06:53

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone

Published on: September 9, 2020

2.9K

Related Experiment Videos

Last Updated: Sep 22, 2025

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
08:57

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

2.1K
A Simple Critical-sized Femoral Defect Model in Mice
09:41

A Simple Critical-sized Femoral Defect Model in Mice

Published on: March 15, 2015

15.3K
Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
06:53

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone

Published on: September 9, 2020

2.9K

Area of Science:

  • Radiology
  • Oncology
  • Pathology

Background:

  • Benign bone lesions are frequently discovered incidentally via imaging (radiographs, CT, MRI).
  • These asymptomatic or minimally symptomatic lesions can mimic aggressive pathologies, complicating diagnosis.
  • Misinterpretation of benign bone lesions as metastases in cancer patients can lead to overtreatment.

Purpose of the Study:

  • To review key imaging features of common and less common benign bone incidentalomas in adults.
  • To aid radiologists in confidently identifying "do-not-touch" benign bone lesions.
  • To differentiate benign bone lesions from sinister pathological conditions.

Main Methods:

  • Review of imaging characteristics for three categories of bone incidentalomas: osteolytic, osteoblastic, and bone protuberances.
  • Focus on distinguishing features to prevent misdiagnosis.

Main Results:

  • Detailed imaging features for selected benign bone lesions are presented.
  • Guidance provided to differentiate benign from malignant bone lesions based on imaging findings.

Conclusions:

  • Accurate identification of benign bone incidentalomas is crucial to avoid unnecessary investigations and interventions.
  • This review equips radiologists with the knowledge to confidently manage these "do-not-touch" lesions.