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Updated: Sep 22, 2025

Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage

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Case 306.

Giuseppe Mamone¹, Settimo Caruso¹, Mariapina Milazzo¹

¹From the Radiology Unit, Department of Diagnostic and Therapeutic Services, IRCCS ISMETT (Mediterranean Institute for Transplantation and Advanced Specialized Therapies), via Tricomi 5, 90127 Palermo, Italy.

|May 23, 2022

Summary

This summary is machine-generated.

This case study details the investigation of an incidental porta hepatis mass in a 61-year-old woman. Advanced imaging and biopsy were used to characterize the mass, exploring potential causes and guiding diagnosis.

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Area of Science:

Hepatobiliary Imaging
Interventional Radiology
Diagnostic Oncology

Background:

A 61-year-old female presented with an incidentally discovered porta hepatis mass.
Past medical history includes pulmonary embolism, pulmonary abscess, and hypothyroidism treated with levothyroxine.
No history of liver disease, prior malignancy, or trauma.

Observation:

Physical examination and laboratory tests, including tumor markers (CEA, CA 19-9), were unremarkable.
Imaging included unenhanced and multiphasic contrast-enhanced CT, with axial and coronal maximum intensity projection reconstructions.
Endoscopic ultrasound-guided fine-needle biopsy and whole-body iodine 131 scintigraphy were performed.

Findings:

CT imaging revealed a mass in the porta hepatis, raising concerns for malignancy.
Endoscopic ultrasound-guided biopsy was performed for definitive characterization.
Iodine 131 scintigraphy was utilized as part of the diagnostic workup.

Implications:

This case highlights the diagnostic challenges and multidisciplinary approach required for incidentally discovered liver region masses.
Accurate characterization through advanced imaging and biopsy is crucial for appropriate patient management.
The study underscores the importance of integrating various diagnostic modalities for complex hepatobiliary presentations.