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Mussel-Glue Derived Peptide-Polymer Conjugates to Realize Enzyme-Activated Antifouling Coatings
Patrick Wilke1, Hans G Börner1
1Laboratory for Organic Synthesis of Functional Systems, Department of Chemistry, Humboldt Universität zu Berlin, Brook-Taylor-Str. 2, 12489 Berlin, Germany.
ACS Macro Letters
|May 24, 2022
Abstract:
Enzyme-activated polymer coatings based on peptide-polymer conjugates are described. Tyrosinase is used to "switch on" adhesive functions of a mussel-glue derived peptide segment, leading to bioconjugates that adhere to steel. The coating resists seawater treatments and modulates surface properties to antifouling surfaces by strongly reducing protein adsorption.

