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Updated: Sep 22, 2025

A Simple and Efficient Protocol for the Catalytic Insertion Polymerization of Functional Norbornenes
Published on: February 27, 2017
Orthogonal Modification of Norbornene-Functional Degradable Polymers
Rebecca J Williams1, Ian A Barker1, Rachel K O'Reilly1
1Department of Chemistry, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, United Kingdom.
Abstract:
Well-defined norbornene-functional poly(carbonate)s were prepared by ring-opening polymerization and utilized as multireactive polymeric scaffolds in a range of postpolymerization modifications. The norbornene-functional handles were shown to undergo facile reaction with azides via a 1,3-dipolar cycloaddition, tetrazines in the inverse electron demand Diels-Alder reaction and thiols via radical thiol-ene coupling. Furthermore, the above-mentioned chemistries were demonstrated in a sequential one-pot, three-step modification reaction illustrating the potential of these polymers as scaffolds to access multifunctionalized materials in an undemanding manner.
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