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High-throughput Identification of Bacteria Repellent Polymers for Medical Devices
Published on: November 5, 2016
ZnO-based antimicrobial coatings for biomedical applications
Vinda Puspasari1, Aga Ridhova1, Angga Hermawan2
1Research Center for Metallurgy, National Research and Innovation Agency, PUSPIPTEK Gd. 470, South Tangerang, Banten, 15315, Indonesia.
Abstract:
Rapid transmission of infectious microorganisms such as viruses and bacteria through person-to-person contact has contributed significantly to global health issues. The high survivability of these microorganisms on the material surface enumerates their transmissibility to the susceptible patient. The antimicrobial coating has emerged as one of the most interesting technologies to prevent growth and subsequently kill disease-causing microorganisms. It offers an effective solution a non-invasive, low-cost, easy-in-use, side-effect-free, and environmentally friendly method to prevent nosocomial infection. Among antimicrobial coating, zinc oxide (ZnO) stands as one of the excellent materials owing to zero toxicity, high biocompatibility to human organs, good stability, high abundancy, affordability, and high photocatalytic performance to kill various infectious pathogens. Therefore, this review provides the latest research progress on advanced applications of ZnO nanostructure-based antibacterial coatings for medical devices, biomedical applications, and health care facilities. Finally, future challenges and clinical practices of ZnO-based antibacterial coating are addressed.
Insights
Zinc oxide (ZnO) nanocoatings offer a safe and effective solution to combat infectious microorganisms on surfaces. This review explores advanced applications of ZnO antibacterial coatings for medical devices and healthcare settings.
Area of Science:
- Materials Science
- Nanotechnology
- Biomedical Engineering
Background:
- Infectious microorganisms transmit rapidly, posing significant global health challenges.
- High microbial survival on surfaces facilitates disease transmission to patients.
- Antimicrobial coatings present a promising strategy to prevent pathogen growth and infection.
Purpose of the Study:
- To review the latest advancements in zinc oxide (ZnO) nanostructure-based antibacterial coatings.
- To highlight the application of these coatings in medical devices, biomedical applications, and healthcare facilities.
- To address future challenges and clinical practices for ZnO-based antibacterial coatings.
Main Methods:
- Literature review of recent research on ZnO nanostructure-based antibacterial coatings.
- Analysis of ZnO material properties relevant to antimicrobial activity (e.g., non-toxicity, biocompatibility, stability, photocatalysis).
- Exploration of diverse applications in healthcare settings.
Main Results:
- ZnO exhibits excellent properties for antimicrobial coatings, including zero toxicity, high biocompatibility, stability, affordability, and photocatalytic efficacy.
- ZnO nanocoatings demonstrate effectiveness against various infectious pathogens.
- Advanced applications span medical devices, biomedical implants, and surfaces in healthcare facilities.
Conclusions:
- ZnO nanostructure-based antibacterial coatings are a viable, eco-friendly solution for preventing nosocomial infections.
- These coatings offer a non-invasive, low-cost, and side-effect-free method for microbial control.
- Further research and clinical integration are needed to fully realize the potential of ZnO coatings in healthcare.
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