Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Retinal Vasculitis in the Setting of <i>Mycobacterium tuberculosis</i> Exposure: Clinical Course and Management of Three Cases.

Case reports in ophthalmology·2025

Same author

Demarcation Laser Photocoagulation for Rhegmatogenous Retinal Detachment: Outcomes in Symptomatic and Asymptomatic Patients.

Case reports in ophthalmology·2025

Same author

Recurrent Intraocular Hemorrhage after Scleral Sutured Intraocular Lens.

Ophthalmology·2025

Same author

PERSISTENT MACULAR HOLE AND CYSTOID MACULAR EDEMA TREATED WITH PARS PLANA VITRECTOMY AFTER FAILURE WITH TOPICAL THERAPY.

Retinal cases & brief reports·2025

Same author

Prevalence of HSV Genomic Signatures Among Acanthamoeba Hosts and Contaminated Lens Cases: A Molecular and Clinical Study.

Investigative ophthalmology & visual science·2025

Same author

Tractional Retinoschisis in Proliferative Diabetic Retinopathy Imaged With Swept-Source Optical Coherence Tomography Angiography.

Ophthalmic surgery, lasers & imaging retina·2025

Search research articles

Related Experiment Video

Updated: Sep 22, 2025

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats

Published on: March 7, 2025

Retinal Detachments Associated With Topical Pilocarpine Use for Presbyopia.

Hasenin Al-Khersan¹, Harry W Flynn¹, Justin H Townsend¹

¹From the Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami Florida, USA.

American Journal of Ophthalmology

|May 24, 2022

Summary

Pilocarpine eye drops used for presbyopia may increase the risk of retinal detachment. Patients should be informed about symptoms like flashes and floaters before starting treatment.

Keywords:

presbyopia retina retinal detachment

More Related Videos

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate

Published on: September 11, 2013

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Related Experiment Videos

Last Updated: Sep 22, 2025

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats

Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats

Published on: March 7, 2025

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate

Retinal Detachment Model in Rodents by Subretinal Injection of Sodium Hyaluronate

Published on: September 11, 2013

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Area of Science:

Ophthalmology
Retinal Diseases
Pharmacology

Background:

Pilocarpine is a miotic agent used to treat glaucoma and presbyopia.
Miotics, including pilocarpine, have been anecdotally linked to retinal detachment.
Presbyopia treatment with pilocarpine is a recent application, necessitating investigation into its side effects.

Observation:

A case series involving 3 eyes from 2 patients presenting with retinal detachment after initiating pilocarpine for presbyopia.
Symptoms included flashes, floaters, and visual field defects, occurring shortly after pilocarpine initiation.
Retinal detachments were observed in various locations, associated with retinal tears.

Findings:

The patients experienced symptoms of retinal detachment within weeks of starting pilocarpine 1.25% drops.
Diagnostic examinations confirmed retinal detachments with associated retinal tears in all affected eyes.
The temporal association suggests a potential causal link between pilocarpine use and retinal detachment.

Implications:

Physicians should counsel patients on the potential risk of retinal detachment before prescribing pilocarpine for presbyopia.
Screening dilated eye examinations may be warranted, especially for myopic patients, to assess retinal detachment risk.
Patient education on recognizing symptoms such as flashes, floaters, and visual field loss is crucial for early detection and intervention.