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Trends in mortality from aortic dissection analyzed from the World Health Organization Mortality Database from 2000
N Abdallah1, C Mouchati2, C Crowley3
1Medical Data Research Collaborative; Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.
International Journal of Cardiology
|May 24, 2022
Summary
Aortic dissection (AD) death rates declined in most countries studied between 2000-2017, but increased in others like Japan. Men consistently showed higher AD mortality rates than women across all nations.
Area of Science:
- Cardiovascular epidemiology
- Public health surveillance
Background:
- Aortic dissection (AD) is a life-threatening condition with significant mortality.
- Understanding global trends in AD mortality is crucial for public health interventions.
Purpose of the Study:
- To analyze trends in aortic dissection (AD) death rates across 23 countries from 2000 to 2017.
- To identify geographical and demographic variations in AD mortality.
Main Methods:
- Extracted mortality data from WHO and CDC WONDER databases.
- Calculated Age Standardized Death Rates (ASDRs) per 100,000 population.
- Assessed trends using locally weighted scatter plot smoother (LOWESS) regression.
Main Results:
- ASDRs for AD decreased in 11 countries for both sexes, including the USA and UK.
- AD mortality increased in 6 countries, notably Japan and Israel, with Japan showing the largest absolute increases.
- In 2017, Japan had the highest ASDRs, while Kyrgyzstan had the lowest. Men consistently exhibited higher AD mortality rates than women globally.
Conclusions:
- Aortic dissection mortality shows a declining trend in many high-income countries but an increasing trend in others.
- Significant geographical variations and a persistent male excess in AD mortality were observed.
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