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Updated: Sep 22, 2025

Acupoint Application as a Traditional Chinese Medicine Treatment for Fatigue Associated with Chronic Obstructive Pulmonary Disease
Published on: September 5, 2025
[Fatigue Doesn't Always have to be caused by SARS-CoV-2: Case Report]
Helmuth Howanietz1, Ulrike Graf1, Theresa Kainz1
1Kindermedizinisches Zentrum Augarten (kiz augarten) Ges.m.b.H., Pazmanitengasse 12/EG, A-1020 Wien, Österreich.
Epstein-Barr virus (EBV) infection can cause significant fatigue in adolescents, distinct from COVID-19. Prompt diagnosis is crucial as some EBV patients develop chronic fatigue syndrome.
Area of Science:
- Infectious Diseases
- Adolescent Medicine
- Virology
Context:
- Adolescent fatigue can be mistaken for other conditions, including COVID-19.
- Epstein-Barr virus (EBV) is a common cause of infectious mononucleosis.
- Distinguishing EBV-induced fatigue from other causes is essential for appropriate management.
Purpose:
- To highlight Epstein-Barr virus (EBV) as a potential cause of significant fatigue in adolescents.
- To emphasize the importance of diagnosing EBV in cases of persistent fatigue.
- To discuss the diagnosis, therapy, and prognosis of EBV-related infectious mononucleosis.
Summary:
- A case report of a 17-year-old female presenting with severe fatigue attributed to Epstein-Barr virus (EBV) infection.
- EBV can cause infectious mononucleosis, leading to prolonged fatigue.
- Up to 13.5% of EBV cases may progress to chronic fatigue syndrome, necessitating accurate diagnosis.
Impact:
- Increases awareness of non-SARS-CoV-2 causes of adolescent fatigue.
- Underscores the need for differential diagnosis in adolescent fatigue presentations.
- Provides insights into managing EBV-induced infectious mononucleosis and its potential long-term sequelae.
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