Related Experiment Video
Updated: Sep 22, 2025
04:48
Control of Eating Behavior Using a Novel Feedback System
Published on: May 8, 2018
11.2K
[Refeeding Syndrome: Where Do We Stand in 2022?]
Katja A Schönenberger1,2, Christa Dürig1, Valentina V Huwiler1,2
1Departement für Diabetologie, Endokrinologie, Ernährungsmedizin und Metabolismus (UDEM), Inselspital, Universitätsspital Bern, Universität Bern, Bern, Schweiz.
Praxis
|May 25, 2022
Summary
Refeeding syndrome, a dangerous condition in malnourished patients, requires more research. Current guidelines exist, but robust trials are needed to clarify management and risk factors.
Area of Science:
- Clinical Nutrition
- Metabolic Medicine
Background:
- Refeeding syndrome is a potentially fatal complication of nutritional support in malnourished individuals.
- Recent consensus manuscripts from ESPEN and ASPEN detailed pathophysiology, diagnosis, and management.
- Existing evidence links refeeding syndrome to adverse clinical outcomes.
Purpose of the Study:
- To provide an evidence-based overview of the current understanding of refeeding syndrome.
- To update the systematic literature search on refeeding syndrome.
- To identify gaps in knowledge regarding management and risk prediction.
Main Methods:
- Updated a systematic literature search initially performed by Friedli et al. in 2015.
- Reviewed consensus manuscripts from major clinical nutrition societies (ESPEN, ASPEN).
- Synthesized existing evidence on pathophysiology, clinical manifestations, prevention, diagnosis, and management.
Main Results:
- Confirmed that refeeding syndrome is associated with negative clinical outcomes.
- Highlighted that many questions regarding the management of refeeding syndrome remain unanswered.
- Identified a lack of robust randomized controlled trials (RCTs) to establish evidence-based practices.
Conclusions:
- Despite recent consensus, significant knowledge gaps persist in refeeding syndrome management.
- A robust randomized controlled trial is urgently needed to address unanswered questions.
- Further research should focus on identifying independent predictors and estimating metabolic risk associated with refeeding syndrome.
Related Concept Videos
01:24Nephrotic Syndrome I : Introduction
41
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
41
01:22Heart Failure VI: Adjunct Therapies
42
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
42
01:26Nephrotic Syndrome II : Assessment and Medical Management
30
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
30
01:19Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
58
The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
58
01:24Nephrotic Syndrome III : Nursing Management
57
Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
57
01:30Acute Pancreatitis II: Clinical Manifestations and Management
187
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
187