Update on the Bidirectional Link Between Diabetes and Periodontitis
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Updated: Sep 22, 2025

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
1Department of Periodontology, Buccal Surgery and Implantology, University of Liège, Liège, Belgium. l.salhi@chuliege.be.
Aim:
To provide an update on the evidence on the bidirectional relationship between periodontitis and diabetes.
Methods:
This narrative review was focused on recent studies between 2015 and 2020. The literature search was performed on PubMed. The inclusion criteria were systematic reviews, consensus reports and controlled trials assessing the effect of diabetes on periodontitis, the effect of periodontitis on diabetes, and the influence of periodontitis non-surgical treatment on diabetes.
Results:
Data concerning the influence of periodontitis on diabetes, and the influence of diabetes on periodontitis were summarized in descriptive tables.
Conclusion:
The control of hyperglycemia in the prevention of periodontitis and the control of periodontitis systemic inflammation in the prevention of diabetes, should be take into account in the treatment planning of both diseases.
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