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Bioactivity inspired C19-diterpenoid alkaloids for overcoming multidrug-resistant cancer

Koji Wada1, Masuo Goto2, Emika Ohkoshi2

  • 1Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Hokkaido University of Science, 4-1, Maeda 7-jo 15-choume, Teine-ku, Sapporo, 006-8585, Japan. kowada@hus.ac.jp.

Journal of Natural Medicines
|May 25, 2022
PubMed

Keywords:
Chemosensitizing effectsDelcosineDelphelineLycoctonine-type C19-diterpenoid alkaloidMultidrug-resistant (MDR) sublineStructure–activity relationship (SAR)

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