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Engineered 2D materials for optical bioimaging and path toward therapy and tissue engineering.

Jeewan C Ranasinghe1, Arpit Jain2, Wenjing Wu1

  • 1Department of Electrical Engineering, The Pennsylvania State University, University Park, PA 16802 USA.

Journal of Materials Research
|May 26, 2022
PubMed
Summary

This review explores two-dimensional (2D) layered materials for biomedical applications, detailing their properties, engineering, and uses. It highlights advances and future opportunities for these nanomaterials in medicine.

Keywords:
2D materialsBiomedical applicationsMachine learningSurface engineering

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Biomedical Engineering

Background:

  • Two-dimensional (2D) layered materials possess unique properties making them promising for biomedical applications.
  • Extensive research is ongoing to understand and utilize these nanomaterials in various medical fields.

Purpose of the Study:

  • To provide a comprehensive review of 2D material-based biomedical applications.
  • To summarize the latest developments, engineering strategies, and future prospects of 2D materials in nanomedicine.

Main Methods:

  • Classification and property analysis of 2D materials.
  • Review of surface and structural engineering techniques (functionalization, defect/strain engineering, heterostructures).
  • Discussion of diverse biomedical applications and the role of machine learning (ML).

Main Results:

  • 2D materials offer exotic properties suitable for advanced biomedical platforms.
  • Various engineering strategies enhance the performance of 2D materials for targeted applications.
  • Machine learning is emerging as a key technology to accelerate development.

Conclusions:

  • Significant progress has been made in 2D material applications in biomedicine.
  • Challenges remain, but opportunities for innovation and future development are substantial.