Neurosurgery in a patient with severe hemophilia B: an experience using eftrenonacog alfa as perioperative management

Olga Benitez Hidalgo1,2, M Fernanda Martinez Garcia1,2, Agustin Bescos Cabestre3

  • 1Hematology Department Experimental Hematology Vall d'Hebron Institute of Oncology (VHIO) Hospital Universitari Vall d'Hebron Vall d'Hebron Barcelona Hospital Campus Barcelona Spain.

Extended half-life FIX (EHL-FIX) concentrates have been developed with the purpose of reducing the frequency of infusions in patients with severe or moderate hemophilia B. We describe the case of a 63-year-old patient with severe hemophilia B (sHB) treated with FIX-Fc fusion protein (rFIXFc) who underwent neurosurgery.

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