Related Experiment Video
Updated: Sep 21, 2025

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
Published on: May 26, 2023
Addition of Local Anesthetic Epidural Infusion Catheter to Intravenous Opioid Analgesia for Postoperative Pain
Shannon M Grap1, Erik B Lehman2, Victoria Heasley1
1Department of Anesthesiology & Perioperative Medicine, Penn State Health Milton S. Hershey Medical Center & Children's Hospital, Hershey, PA.
Insights
For pediatric patients undergoing VATS surgery, epidural catheters combined with IV opioids did not significantly reduce morphine equivalents or pain scores compared to IV opioids alone. Further research is needed to explore potential reasons for this finding.
Area of Science:
- Pediatric Anesthesiology
- Thoracic Surgery
- Pain Management
Background:
- Minimally invasive video-assisted thoracoscopic surgery (VATS) in children often requires effective postoperative pain management.
- Epidural analgesia is a potential strategy to reduce opioid use and systemic side effects in pediatric patients.
Purpose of the Study:
- To compare the efficacy of epidural analgesia combined with intravenous opioids versus intravenous opioids alone in pediatric patients following VATS.
- To evaluate differences in total morphine equivalents (MEQ) and pain scores between the two analgesic approaches.
Main Methods:
- Retrospective chart review of pediatric patients (1 month to 18 years) undergoing noncardiac thoracic VATS.
- Patients were divided into two groups: those receiving epidural infusion catheters and those not (nonepidural group).
- Both groups received intravenous systemic opioids; primary outcomes were perioperative MEQ and pain scores.
Main Results:
- Ninety-two patients were analyzed (22 in epidural group, 70 in nonepidural group).
- No statistically significant differences in MEQ requirements or pain scores were observed between groups intraoperatively, in the PACU, or at 24 and 48 hours postoperatively.
- Presence of infection or empyema was a significant factor influencing the decision to avoid epidural placement (P=.003).
Conclusions:
- Epidural catheter use did not significantly alter perioperative opioid consumption or postoperative pain scores in pediatric VATS patients compared to intravenous opioids alone.
- Further investigation is warranted to determine if factors like epidural catheter malposition or inadequate coverage contributed to the lack of observed benefit.
Purpose:
Postoperative analgesia following minimally invasive video assisted thoracoscopic surgery (VATS) in pediatric patients may involve intravenous opioid analgesics and continuous local anesthetic infusions via an epidural infusion catheter. The use of epidural catheters may avoid systemic side effects of intravenous opioids in this vulnerable population.
Design:
Our primary aim was to compare total morphine equivalents (MEQ) required, and pain scores between local anesthetic epidural infusion catheters combined with intravenous opioids, versus intravenous opioids alone in pediatric patients following VATS procedure.
Methods:
Following Institutional Review Board approval, we performed a retrospective chart review of children (ages 1 month to 18 years) who underwent VATS procedure for noncardiac thoracic surgery. Based on the postoperative analgesic technique used, the study population was divided into two groups that is, epidural group and nonepidural group. Both groups received intravenous systemic opioids. The primary outcome variables were total MEQ required and pain scores in the perioperative period.
Findings:
Ninety-two patients were included in the study. Of these, 22 patients belonged to the epidural group versus 70 patients to the nonepidural group. There was no statistical difference in MEQ requirements or pain scores between the groups intraoperatively (P = .304), in the postanesthesia care unit (P = .166), or at postoperative time intervals of 24 hours (P = .805) and 48 hours (P = .844). The presence of infection or empyema was a significant factor for the avoidance of epidural placement by providers (P = .003).
Conclusions:
There was no significant difference in the perioperative MEQ or postoperative pain scores between the epidural catheter group and the nonepidural group. More research is necessary to determine if this could be due to epidural catheter malposition and/or inadequate dermatomal coverage of surgical chest tubes.
Related Concept Videos
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...
Local Anesthetics: Clinical Application as Spinal Anesthesia
Parenteral Anesthetics: Overview
Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia
Local Anesthetics: Pharmacokinetics

