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Updated: Aug 10, 2026

Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro
Published on: July 5, 2017
Selection and Optimization of an Innovative Polysaccharide-Based Carrier to Improve Anthocyanins Stability in Purple
Lucia Ferron1,2, Chiara Milanese3, Raffaella Colombo1
1Drug Sciences Department, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Abstract:
The extraction process of alcohol-insoluble polysaccharides from exhausted Moradyn cob (Zea mays L. cv. Moradyn) (EMCP), camelina cake (Camelina sativa L. Crantz) (CCP), and common bean seeds (Phaseolus vulgaris L.) (CBP) was investigated and optimized by Response Surface Methodology. Each fraction was tested at different core/carrier ratios in the encapsulation of Moradyn cob extract (MCE), a rich source of antioxidant anthocyanins, and the obtained ingredients were screened for their encapsulation efficiency (EE%) and extraction process sustainability. The ingredients containing 50% and 75% CCP had EE% higher than 60% and 80%, respectively, and were selected for further studies. Preliminary structural analysis indicated CCP was mostly composed of neutral polysaccharides and proteins in a random-coiled conformation, which was also unchanged in the ingredients. CCP-stabilizing properties were tested, applying an innovative stress testing protocol. CCP strongly improved MCE anthocyanins solid-state stability (25 °C, 30% RH), and therefore it could be an innovative anthocyanins carrier system.
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