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Ag Nanoparticles for Biomedical Applications-Synthesis and Characterization-A Review
Alexandra Nicolae-Maranciuc1, Dan Chicea1, Liana Maria Chicea2
1Research Center for Complex Physical Systems, Faculty of Sciences, Lucian Blaga University of Sibiu, Dr. Ion Raţiu Street 5-7, 550012 Sibiu, Romania.
International Journal of Molecular Sciences
|May 28, 2022
Summary
Silver nanoparticles are versatile for biomedical uses due to their antibacterial properties. This review covers their synthesis, including green methods, and characterization for applications like infection treatment and drug delivery.
Area of Science:
- Nanotechnology
- Materials Science
- Biomedical Engineering
Background:
- Silver nanoparticles (AgNPs) are extensively researched for their potent antibacterial properties.
- Their functionalization enhances stability, making them ideal for diverse biomedical applications.
- AgNPs can be synthesized in various shapes and sizes, influencing their efficacy.
Purpose of the Study:
- To provide a comprehensive review of silver nanoparticle synthesis methods.
- To discuss the characterization techniques essential for evaluating AgNPs in antibacterial contexts.
- To highlight the significance of AgNPs in infection treatments, wound healing, and drug delivery systems.
Main Methods:
- Review of existing literature on silver nanoparticle synthesis.
- Analysis of various fabrication conditions affecting nanoparticle morphology and size.
- Brief overview of common characterization techniques for nanoparticle analysis.
Main Results:
- Silver nanoparticles exhibit significant antibacterial activity.
- Functionalization strategies improve stability and suitability for biomedical applications.
- Synthesis methods, including green synthesis, yield nanoparticles with diverse characteristics.
Conclusions:
- Silver nanoparticles are promising for biomedical applications due to their antibacterial properties and tunable characteristics.
- Understanding synthesis and characterization is crucial for optimizing their use in medicine.
- Further research into green synthesis and advanced characterization will enhance AgNP applications.

