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Polypropylene Hollow Fiber Membrane by Dissolution-Inducing Pore Methods
1The State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, China.
Membranes
|May 28, 2022
Summary
A new dissolution-induced pore method created advanced polypropylene hollow fiber membranes. These membranes prevent plasma leakage, offering a promising, low-cost material for extracorporeal membrane oxygenation.
Area of Science:
- Biomaterials Engineering
- Polymer Science
- Membrane Technology
Background:
- Plasma leakage is a major limitation in developing effective polypropylene membranes for oxygenation.
- Existing membrane technologies face challenges in preventing leakage and maintaining high gas flux.
Purpose of the Study:
- To develop a novel polypropylene hollow fiber membrane with enhanced anti-leakage properties.
- To optimize membrane fabrication using a dissolution-induced pore method.
- To evaluate the performance and cost-effectiveness for extracorporeal membrane oxygenation (ECMO).
Main Methods:
- Melt-blending and extruding polypropylene with polyvinyl chloride.
- Dissolving polyvinyl chloride using N, N-dimethylacetamide to create porous polypropylene.
- Investigating parameter influences on membrane flux and mechanical properties.
- Assessing polyvinyl chloride recovery feasibility.
Main Results:
- Achieved zero plasma penetration within 6 hours.
- High gas flux of 189,000 L/(m²·h·0.1 MPa).
- Excellent mechanical properties: 65 MPa strength at break and 890% elongation at break.
- Polyvinyl chloride recovery exceeding 99%.
Conclusions:
- The dissolution-induced pore method successfully produced robust, leak-proof polypropylene hollow fiber membranes.
- This material is a promising, low-cost alternative for extracorporeal membrane oxygenation.
- The developed membranes offer significant benefits for patients with limited financial resources.

