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Management of Hypertension with Female Sexual Dysfunction
1Bioscience Department, Rocky Vista University College of Osteopathic Medicine, Ivins, UT 84738, USA.
Female sexual dysfunction (FSD) is more common in women with hypertension. Beta-blockers may worsen FSD, while angiotensin receptor blockers (ARBs) show benefits. Managing blood pressure is crucial for treating FSD in hypertensive women.
Area of Science:
- Cardiology
- Endocrinology
- Pharmacology
Background:
- Female sexual dysfunction (FSD) in hypertensive women is understudied compared to men.
- The effects of antihypertensive medications on female sexual function require clarification.
Purpose of the Study:
- To review the impact of hypertension and its treatments on female sexual function.
- To identify antihypertensive agents affecting FSD and recommend management strategies.
Main Methods:
- Systematic review of randomized double-blind clinical trials and cross-sectional studies.
- Analysis of studies published between 1991 and 2021.
Main Results:
- Hypertensive women exhibit higher rates of FSD compared to normotensive women.
- Beta-blockers are associated with negative effects on female sexual function.
- Angiotensin receptor blockers (ARBs) demonstrate a beneficial impact on female sexual function.
Conclusions:
- Controlling blood pressure is paramount for treating FSD in hypertensive individuals.
- ARBs are preferred for managing FSD in hypertensive women.
- Specific treatments like flibanserin, bremelanotide, ospemifene, and hormone supplements may be considered based on menopausal status.
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