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Metallic Engineered Nanomaterials and Ocular Toxicity: A Current Perspective.

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Engineered nanomaterials (ENM) in products pose risks to eye health. This review examines metallic ENM ocular toxicity and therapeutic uses in ophthalmology.

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Area of Science:

  • Ophthalmology
  • Nanotechnology
  • Toxicology

Background:

  • The ocular surface acts as a barrier against environmental factors.
  • Engineered nanomaterials (ENM), especially metallic ENMs, are increasingly used in consumer products and therapeutics.
  • Ocular exposure to metallic ENMs is common, but their effects on eye health are not fully understood.

Purpose of the Study:

  • To review current literature on the ocular toxicity of metallic ENMs.
  • To assess the risks and benefits of metallic ENMs in ophthalmic therapeutic applications.
  • To inform product usage and patient care regarding ocular exposure to metallic ENMs.

Main Methods:

  • Literature review of in vitro and in vivo studies.
  • Analysis of commercial and therapeutic applications of metallic ENMs.
  • Evaluation of potential adverse effects on ocular tissues.

Main Results:

  • Metallic ENMs are prevalent in cosmetics and sunscreens, leading to potential ocular exposure.
  • Metallic ENMs possess properties making them suitable for therapeutic uses in ophthalmology.
  • Further research is needed to fully understand the ocular toxicity of metallic ENMs.

Conclusions:

  • Increased use of metallic ENMs necessitates a thorough understanding of their ocular safety.
  • Balancing the risks and benefits of metallic ENMs in ophthalmology is crucial.
  • Continued research is vital for protecting ocular health in the face of advancing nanotechnology.