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Updated: Sep 21, 2025

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
23:33

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation

Published on: February 28, 2012

83.9K

Left atrial appendage closure using WATCHMAN device in chronic kidney disease and end-stage renal disease patients

Shakeel Jamal1, Mohsin Sheraz Mughal2, Asim Kichloo1

  • 1Department of Internal Medicine, Central Michigan University, College of Medicine, Mount Pleasant, Michigan, USA.

Pacing and Clinical Electrophysiology : PACE
|May 28, 2022
PubMed

Insights

Patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) undergoing left atrial appendage occlusion (LAAC) with the Watchman device have similar outcomes to those without kidney disease. This includes comparable in-hospital mortality and complication rates for Watchman procedures.

Area of Science:

  • Cardiology
  • Nephrology
  • Medical Devices

Background:

  • Chronic kidney disease (CKD) and end-stage renal disease (ESRD) are significant risk factors for atrial fibrillation (AF).
  • Left atrial appendage occlusion (LAAC) with the Watchman device is an alternative to anticoagulation for stroke prevention in AF patients.
  • Limited data exists on the safety and utilization of LAAC in CKD/ESRD patients.

Purpose of the Study:

  • To evaluate the utilization and periprocedural safety of Watchman LAAC in patients with and without CKD/ESRD.
  • To compare inpatient mortality, length of stay, and cost of stay for Watchman procedures in patients with and without CKD/ESRD.

Main Methods:

  • Retrospective review of the National Inpatient Sample (NIS) database from 2016-2017.
  • Inclusion criteria: adult patients undergoing Watchman LAAC procedure.
  • Comparison of outcomes between patients with and without CKD/ESRD diagnoses.

Main Results:

  • 19.66% of 16,505 Watchman procedures were performed in patients with CKD/ESRD.
  • No statistically significant differences in inpatient mortality, length of stay, or cost of stay were observed between groups.
  • Periprocedural cerebrovascular accident rates were similar in both patient cohorts.

Conclusions:

  • Watchman LAAC demonstrates similar safety and efficacy in patients with CKD/ESRD compared to those without kidney disease.
  • The procedure is a viable option for stroke risk reduction in AF patients with CKD/ESRD.
  • Further research may explore long-term outcomes in this population.
Abstract

Keywords:
atrial fibrillationchronic kidney diseaseend-stage renal diseaseleft atrial appendage closure

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