Related Experiment Video
Updated: Sep 21, 2025
09:32
Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
Published on: September 26, 2019
7.3K
Contact dermatitis in children caused by diabetes devices
Catarina Alves da Silva1, Anne Bregnhøj1, Martin Mowitz2
1Department of Dermatology and Venereology, Aarhus University Hospital, Aarhus, Denmark.
Contact Dermatitis
|May 31, 2022
Summary
Localized contact dermatitis in children using insulin pumps and glucose monitors is often caused by isobornyl acrylate (IBOA) and benzoyl peroxide (BP). Further investigation into device materials is crucial for identifying unknown allergens.
Area of Science:
- Dermatology
- Allergology
- Pediatrics
Background:
- Insulin pumps and glucose monitoring devices improve diabetes management but are linked to adverse skin reactions.
- Cutaneous reactions associated with these diabetes devices are increasingly reported.
Purpose of the Study:
- Identify the specific allergens causing localized contact dermatitis in pediatric patients using insulin pumps and glucose monitoring devices.
Main Methods:
- Retrospective analysis of 15 pediatric patients undergoing patch testing for skin reactions.
- Investigated reactions to components of insulin pumps and glucose monitoring devices.
Main Results:
- 10 out of 15 patients showed positive patch test reactions to device materials.
- Isobornyl acrylate (IBOA) was identified as an allergen in 7 patients, and benzoyl peroxide (BP) in 5.
- Reactions to adhesive remover wipes and EMLA plaster were also noted.
Conclusions:
- Isobornyl acrylate (IBOA) and benzoyl peroxide (BP) are significant allergens in pediatric patients using diabetes devices.
- The study highlights the need for complete chemical composition disclosure of medical devices to identify unknown allergens.
Related Concept Videos
01:22Diabetes Mellitus: Overview and Type I Subtype
3.3K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
3.3K
01:23Skin Diseases and Disorders
4.3K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
4.3K
01:22Diabetes Mellitus: Type 2 and Gestational
3.0K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
3.0K
01:20Pathophysiology of Diabetes
1.3K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
1.3K
01:15Diabetes: Symptoms, Diagnosis, and Complications
723
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
723
01:25Immunodeficiency Diseases
1.2K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
There are three main causes of immunodeficiency...
1.2K