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A Rapid, Multiplex Dual Reporter IgG and IgM SARS-CoV-2 Neutralization Assay for a Multiplexed Bead-Based Flow Analysis System
Published on: April 6, 2021
Novel Assays for Molecular Detection of Severe Acute Respiratory Syndrome Coronavirus 2
Kyle G Rodino1, Kenneth P Smith2, Matthew A Pettengill3
1Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, 4th Floor Gates Building, Philadelphia, PA 19104, USA; Clinical Microbiology Laboratory, Hospital of the University of Pennsylvania, Philadelphia, PA, USA. Electronic address: https://twitter.com/KGRodinoPhD.
Abstract:
From the onset of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/COVID-19 pandemic, there has been a major emphasis on molecular laboratory tests for the virus. Shortages in various testing supplies, the desire to increase testing capacity, and a push to make point-of-care or home-based testing available have fostered considerable innovation for SARS-CoV-2 molecular diagnostics, advancements likely to be applicable to other diagnostic uses. The authors attempt to cover some of the most compelling novel types of molecular assays or novel approaches in adapting established molecular methodologies for SARS-CoV-2 detection or characterization.

