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Association between arteriovenous access flow and ventricular function: A cross-sectional study
Rachmat Ageng Prastowo1, Johanes Nugroho Eko Putranto1, Iswanto Pratanu1
1Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Airlangga - Dr. Soetomo General Academic Hospital, Jl. Mayjend Prof. Dr. Moestopo No 4-6, Surabaya, East Java, 60286, Indonesia.
Insights
High arteriovenous access flow in hemodialysis patients is linked to impaired cardiac function. This study found reduced left and right ventricular function in patients with high access flow, highlighting a critical connection for kidney disease management.
Area of Science:
- Cardiovascular Medicine
- Nephrology
- Medical Imaging
Background:
- Permanent hemodialysis access, while beneficial, presents risks like flow disturbances and infection.
- These complications can potentially lead to impaired cardiac function.
- The specific relationship between arteriovenous access flow and cardiac function in hemodialysis patients remains unclear.
Purpose of the Study:
- To analyze the relationship between artificial arteriovenous access flow and left and right ventricular function.
- To investigate cardiac function in patients with chronic kidney disease (CKD) undergoing hemodialysis.
Main Methods:
- Cross-sectional study with consecutive sampling of 47 CKD patients undergoing hemodialysis.
- Doppler ultrasound used to measure arteriovenous access flow.
- Transthoracic echocardiography employed to assess left and right ventricular function.
Main Results:
- 55.3% of patients exhibited high arteriovenous access flow.
- Patients with high access flow showed significantly lower left ventricular ejection fraction compared to the non-high-flow group (p < 0.05).
- The high-flow group also demonstrated significantly lower right ventricle fractional area changes (p < 0.05).
Conclusions:
- Arteriovenous access flow, measured by Doppler ultrasonography, is significantly associated with impaired left and right ventricular systolic function.
- Echocardiographic parameters indicate a link between high access flow and reduced cardiac performance in hemodialysis patients.
Background:
Permanent hemodialysis access comes with a myriad of problems on top of the well-known benefits; flow disturbances, risk of infection and revision being among them. All of these could eventually lead to impaired cardiac function. Even so, the relationship between impaired cardiac function due to arteriovenous access in patients undergoing hemodialysis has not been clearly described. This study aimed to analyze the relationship of flow in an artificial arteriovenous access with left and right ventricular function in patients with chronic kidney disease (CKD) undergoing hemodialysis at a referral hospital in Indonesia.
Material And Methods:
This was a cross sectional study with consecutive sampling technique. Samples were patients with CKD undergoing hemodialysis at Dr. Soetomo General Hospital from December 2021to January 2022. A total of 47 patients who met the inclusion criteria underwent Doppler ultrasound to assess arteriovenous access flow and transthoracic echocardiography to assess left and right ventricle function.
Results:
From 47 patients, 26 (55.3%) had high arteriovenous access flow. The clinical characteristics of the patients between the high and low arteriovenous access flow groups were not significantly different. We found that the value of left ventricular ejection fraction in the non-high-flow access group was significantly higher than the high-flow access group (p < 0.05). Other than that, the median right ventricle fractional area changes in the non-high-flow access group was also higher than the high-flow access group (p < 0.05).
Conclusion:
Arteriovenous access flow as measured by Doppler ultrasonography has a significant relationship with impaired left and right ventricular functions based on systolic function parameters from echocardiography.
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