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Association between arteriovenous access flow and ventricular function: A cross-sectional study.

Rachmat Ageng Prastowo1, Johanes Nugroho Eko Putranto1, Iswanto Pratanu1

  • 1Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Airlangga - Dr. Soetomo General Academic Hospital, Jl. Mayjend Prof. Dr. Moestopo No 4-6, Surabaya, East Java, 60286, Indonesia.

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|May 31, 2022
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Summary

High arteriovenous access flow in hemodialysis patients is linked to impaired cardiac function. This study found reduced left and right ventricular function in patients with high access flow, highlighting a critical connection for kidney disease management.

Keywords:
Arteriovenous anastomosisHemodialysisLeft ventricular functionRight ventricular function

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Area of Science:

  • Cardiovascular Medicine
  • Nephrology
  • Medical Imaging

Background:

  • Permanent hemodialysis access, while beneficial, presents risks like flow disturbances and infection.
  • These complications can potentially lead to impaired cardiac function.
  • The specific relationship between arteriovenous access flow and cardiac function in hemodialysis patients remains unclear.

Purpose of the Study:

  • To analyze the relationship between artificial arteriovenous access flow and left and right ventricular function.
  • To investigate cardiac function in patients with chronic kidney disease (CKD) undergoing hemodialysis.

Main Methods:

  • Cross-sectional study with consecutive sampling of 47 CKD patients undergoing hemodialysis.
  • Doppler ultrasound used to measure arteriovenous access flow.
  • Transthoracic echocardiography employed to assess left and right ventricular function.

Main Results:

  • 55.3% of patients exhibited high arteriovenous access flow.
  • Patients with high access flow showed significantly lower left ventricular ejection fraction compared to the non-high-flow group (p < 0.05).
  • The high-flow group also demonstrated significantly lower right ventricle fractional area changes (p < 0.05).

Conclusions:

  • Arteriovenous access flow, measured by Doppler ultrasonography, is significantly associated with impaired left and right ventricular systolic function.
  • Echocardiographic parameters indicate a link between high access flow and reduced cardiac performance in hemodialysis patients.