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Multi-timescale Microscopy Methods for the Characterization of Fluorescently-labeled Microbubbles for Ultrasound-Triggered Drug Release
Published on: June 12, 2021
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Next-Generation Colloidal Materials for Ultrasound Imaging Applications
Mark Louis P Vidallon1, Boon Mian Teo1, Alexis I Bishop2
1School of Chemistry, Monash University, Clayton, Victoria, Australia.
Ultrasound in Medicine & Biology
|May 31, 2022
Summary
New colloidal systems enhance ultrasound imaging and drug delivery. Researchers are developing advanced microbubbles and droplets for targeted therapies and multimodal imaging applications.
Area of Science:
- Biomedical Engineering
- Materials Science
- Acoustics
Background:
- Ultrasound is crucial for diagnostic imaging.
- Current ultrasound contrast agents have limitations.
- Novel colloidal systems offer enhanced properties and functionalities.
Purpose of the Study:
- To review recent advancements in colloidal systems for ultrasound contrast enhancement.
- To explore applications beyond imaging, including targeted drug delivery and multimodal imaging.
- To highlight the use of biologically derived and bio-inspired materials in these systems.
Main Methods:
- Review of current literature on colloidal systems for ultrasound.
- Analysis of microbubbles, emulsion droplets, and particle systems.
- Discussion of materials science, chemistry, and physics principles.
Main Results:
- Development of advanced colloidal systems with improved ultrasound contrast.
- Emergence of multi-responsive and application-specific colloidal assemblies.
- Integration of biopolymers and biomembranes for enhanced biocompatibility and functionality.
Conclusions:
- Next-generation colloidal systems show significant promise for biomedical applications.
- These systems offer potential for advanced imaging-guided treatments.
- Future research directions include overcoming challenges and exploring new material designs.
