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Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Nanotechnology

Background:

  • Block copolymers with liquid crystalline (LC) mesogens offer unique self-assembly properties.
  • Janus nanoparticles (NPs) possess distinct functionalities on different surfaces.
  • Azobenzene derivatives are known photo-responsive molecules.

Purpose of the Study:

  • To develop novel snowman-like Janus nanoparticles (NPs) using azobenzene liquid crystalline block copolymers.
  • To investigate the light-induced morphological changes and recovery of these Janus NPs.
  • To explore the potential of these NPs for programmable payload delivery and release.

Main Methods:

  • Emulsion solvent evaporation technique was employed to synthesize Janus NPs.
  • The NPs feature an azobenzene-containing poly(methacrylate) (PMAAz) head in a smectic LC phase.
  • Trans/cis isomerization of azobenzene under UV and visible light irradiation was utilized to control NP shape and LC state.

Main Results:

  • Janus NPs with a snowman-like morphology were successfully prepared.
  • UV irradiation induced trans/cis transformation in the PMAAz head, causing it to become amorphous and enlarge.
  • The enlarged PMAAz head engulfed the other NP head, and visible light restored the original shape and LC state.

Conclusions:

  • A light-triggered, reversible shape-changing mechanism for Janus NPs was demonstrated.
  • This strategy enables programmable loading and release of payloads using light as a remote trigger.
  • The developed Janus NPs hold promise for advanced applications in drug delivery and nanotechnology.