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Statistical Analysis of IABP-Surgery Data with the Co-use of Anticoagulants, Pulse of Dorsalis Pedis Artery, D-Dimer

Huali Chen1,2, Zhoumin Shen1, Yan Zhang2,3

  • 1Quality Control Office of Nursing Department, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, China.

Frontiers in Surgery
|June 2, 2022
PubMed

Insights

Intra-aortic balloon pump (IABP) patient data reveal significant differences in dorsalis pedis artery pulsation based on sex and anticoagulant use. Coagulation function positively correlates with D-dimer, impacting prognosis.

Area of Science:

  • Cardiovascular Medicine
  • Medical Diagnostics
  • Pharmacology

Background:

  • Intra-aortic balloon pump (IABP) therapy is critical for managing cardiovascular emergencies.
  • Understanding factors influencing peripheral circulation and coagulation in IABP patients is essential for optimizing outcomes.
  • Limited data exist on the interplay between anticoagulation, arterial pulsation, and coagulation markers in this patient cohort.

Purpose of the Study:

  • To investigate the relationship between anticoagulant use, dorsalis pedis artery pulsation, D-dimer levels, and coagulation function in IABP patients.
  • To identify potential predictors of prognosis and complications.
  • To analyze sex-based differences in peripheral circulation parameters.

Main Methods:

  • Retrospective analysis of data from 52 hospitalized IABP patients.
  • Collection of data on anticoagulant use, dorsalis pedis artery pulsation, D-dimer levels, and coagulation function.
  • Statistical analysis including nonparametric tests, linear regression, adjustment effect analysis, and chi-square tests.

Main Results:

  • Significant sex-based differences were observed in dorsalis pedis artery pulsation.
  • A significant positive correlation was found between coagulation function and D-dimer levels.
  • D-dimer's influence on prognosis varied significantly with different levels of dorsalis pedis artery pulse.
  • Anticoagulant type demonstrated significant differences in dorsalis pedis artery pulsation.

Conclusions:

  • Dorsalis pedis artery pulsation is influenced by sex, anticoagulant therapy, and D-dimer levels in IABP patients.
  • Coagulation status and D-dimer are closely linked and affect patient prognosis.
  • These findings highlight the importance of monitoring peripheral circulation and coagulation parameters in IABP management.

Keywords:
SPSSanalysisintra-aortic balloon pumpingnursing careretrospective study

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