Interventions for Congenital Atrioventricular Valve Dysfunction: JACC Focus Seminar.

Area of Science:

• Cardiology
• Interventional Cardiology
• Congenital Heart Disease Management

Background:

• Advances in congenital heart disease (CHD) care have significantly increased patient survival.
• Catheter-based interventions have been key to these improvements.
• However, interventions for congenital atrioventricular (AV) valve lesions remain challenging due to patient size and anatomy.

Purpose of the Study:

• To explore the evolving landscape of transcatheter interventions for atrioventricular (AV) valve disease in adult congenital heart disease (CHD) patients.
• To highlight the potential of new transcatheter techniques and technologies for managing congenital AV valve lesions.
• To discuss the translation of these advancements from adult non-CHD populations to adult CHD patients.

Main Methods:

• Review of current literature on transcatheter heart valve technologies.
• Analysis of the application of these technologies in adult patients without CHD.
• Assessment of the emerging translation of these practices to adult CHD populations.

Main Results:

• Transcatheter heart valve technologies are rapidly advancing.
• Many devices for AV valve repair and replacement are under investigation in non-CHD adults.
• Initial translation of select practices to adult CHD patients has commenced.

Conclusions:

• Transcatheter AV valve interventions present significant opportunities for the growing adult CHD population.
• These novel approaches may overcome limitations of traditional surgical methods for congenital AV valve lesions.
• The ongoing revolution in transcatheter therapies is poised to reshape the management of adult CHD.