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Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
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Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
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Antiasthma Drugs: Leukotriene Modifiers01:19

Antiasthma Drugs: Leukotriene Modifiers

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Leukotriene modifiers, or cysteinyl leukotriene receptor antagonists, are medications used to manage chronic asthma. These agents target specific inflammatory mediators produced during arachidonic acid metabolism, an essential process in generating inflammation in the body.
Leukotriene modifiers work through two distinct mechanisms:
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Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
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Corrigendum to "Synbiotic Bactecal® reduces airway obstruction, sputum eosinophils and IL-4 but increases sputum IL-8 in patients with uncontrolled asthma" [Cytokine 202 (2026) 157145].

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Related Experiment Video

Updated: Sep 21, 2025

Probiotic Studies in Neonatal Mice Using Gavage
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[Probiotics in asthma treatment].

C Moermans1,2, S Graff1,2, S Gerday1

  • 1Groupe de Recherche GIGA I3, ULiège, Belgique.

Revue Medicale De Liege
|June 3, 2022
PubMed
Summary
This summary is machine-generated.

Probiotics may offer new therapeutic approaches for asthma by modulating the gut microbiome. This review explores their potential in asthma prevention and treatment due to their anti-inflammatory properties.

Keywords:
ImmunityProbioticsAsthma

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Area of Science:

  • Immunology
  • Microbiology
  • Respiratory Medicine

Background:

  • Asthma is a widespread chronic inflammatory airway disease.
  • Gut microbiota dysregulation is linked to immune development and asthma emergence.
  • Alterations in intestinal microbiota are observed in individuals with asthma.

Purpose of the Study:

  • To review the current knowledge on probiotic use for asthma.
  • To explore probiotics as potential therapeutic agents for asthma.

Main Methods:

  • Literature review of studies on probiotics and asthma.
  • Analysis of the role of gut microbiota in asthma pathogenesis.
  • Evaluation of probiotic properties, including anti-inflammatory and immunoregulatory effects.

Main Results:

  • Probiotics can modulate the gut microbiome.
  • Probiotics demonstrate anti-inflammatory and immunoregulatory properties.
  • Probiotics are generally well-tolerated and safe.

Conclusions:

  • Probiotic use in asthma prevention and treatment is a promising area.
  • Probiotics may offer novel therapeutic perspectives for managing asthma.
  • Further research is warranted to fully elucidate the role of probiotics in asthma.