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Updated: Sep 21, 2025

Laparoscopic Left Hemihepatectomy Combined with Caudate Lobe Resection
Published on: April 11, 2025
[Indications for lymph node dissection in hepatocellular carcinoma]
S E Voskanyan1, E S Chuchuev2, V S Rudakov1
1Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russia.
Objective:
To determine the indications for lymph node dissection in patients with hepatocellular carcinoma.
Material And Methods:
The study included 105 patients with hepatocellular carcinoma who underwent dissection of 8, 9, 12, 13 and 16a2 groups of lymph nodes. Concomitant liver diseases were not a contraindication for lymph node dissection. Immediate and long-term treatment outcomes were retrospectively analyzed.
Results:
Lymph node dissection did not affect the number of postoperative complications (p=0.83) and mortality (p=0.34). The number of tumors (p=0.02) and concomitant liver diseases (p=0.05) significantly affected lymph node metastatic lesions. Metastases were found only in lymph nodes >1 cm. Metastatic lesions of lymph nodes in hepatoduodenal ligament and retropancreatic zone were the most common. However, 5 patients had metastatic lesions of aortocaval and celiac lymph nodes without metastases in hepatoduodenal ligament. Overall 5-year survival of patients with lymph node metastases after total resection was 32.4%. It is a better result compared to other treatments.
Conclusion:
There was no significant effect of lymph node dissection on immediate postoperative results regardless concomitant pathology. Lymph node dissection is recommended for patients with a high risk of metastasis or lymph nodes metastases.

