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Updated: Sep 21, 2025

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Living Anionic Copolymerization of 1-(Alkylsulfonyl)aziridines to Form Poly(sulfonylaziridine) and Linear
Louis Reisman1, Canisius P Mbarushimana1, S Joel Cassidy1
1Department of Chemistry, The University of Alabama, Tuscaloosa, Alabama 35487-0336, United States.
Abstract:
The anionic ring-opening copolymerization of 1-(methylsulfonyl)aziridine (MsAz) and 1-(sec-butylsulfonyl)aziridine (BsAz) produces a soluble random copolymer P(MsAz-r-sBsAz), which can subsequently be converted to linear poly(ethylenimine) (lPEI). The copolymerization of MsAz and BsAz is living and allows for the synthesis of copolymers with low molecular weight distributions. Sequential anionic polymerization of MsAz and BsAz with 2-methyl-1-(methylsulfonyl)aziridine (MsMAz) creates P(MsAz-r-sBsAz)-b-P(MeMsAz). Removal of the sulfonyl groups from P(MsAz-r-sBsAz)-b-P(MsMAz) gives lPEI-b-poly(propylenimine). For the first time, lPEI can be synthesized by a controlled anionic polymerization.
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