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Oral Lichen Planus Treated With Plasma Rich in Growth Factors
Eduardo Anitua1, Asier Eguia1, Mohammad Hamdan Alkhraisat1
1University Institute for Regenerative Medicine and Oral Implantology (UPV/EHU-Fundación Eduardo Anitua), Vitoria-Gasteiz, Álava, Spain. Dr. Eguia also is from the University of the Basque Country UPV/EHU, Leioa, Vizcaya, Spain. Dr. Alkhraisat also is from BTI Biotechnology Institute, Vitoria-Gasteiz. Dr. Anitua is the Scientific Director of BTI Biotechnology Institute and the President of Eduardo Anitua Foundation. Drs. Eguia and Piñas are researchers at the Eduardo Anitua Foundation. Dr. Piñas also served as a speaker for BTI Biotechnology Institute. Dr. Alkhraisat is a researcher at BTI Biotechnology Institute.
Abstract:
The use of plasma rich in growth factors (PRGF) is a treatment for erosive oral lichen planus (OLP) resistant to steroid therapy. An anonymous database at a clinical center was reviewed to collect demographic data, lesion type, treatment protocol, number of infiltrations, pain score, and healing time of the lesions. Fifteen patients were included in this study. All patients were diagnosed with erosive OLP. The lesions in all patients were refractory to steroid therapy (topical and systemic). Results showed that the use of plasma rich in growth factors (PRGF) could be a promising alternative for the treatment of erosive OLP refractory to steroid therapy, though new prospective studies are needed to confirm these preliminary observations.
