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Updated: Sep 20, 2025

Three-dimensional Optical-resolution Photoacoustic Microscopy
Published on: May 3, 2011
Multi-angle data acquisition to compensate transducer finite size in photoacoustic tomography
Soheil Hakakzadeh1, Moein Mozaffarzadeh2, Seyed Masood Mostafavi1
1Department of Electrical Engineering, Sharif University of Technology, Tehran, Iran.
Abstract:
In photoacoustic tomography (PAT) systems, the tangential resolution decreases due to the finite size of the transducer as the off-center distance increases. To address this problem, we propose a multi-angle detection approach in which the transducer used for data acquisition rotates around its center (with specific angles) as well as around the scanning center. The angles are calculated based on the central frequency and diameter of the transducer and the radius of the region-of-interest (ROI). Simulations with point-like absorbers (for point-spread-function evaluation) and a vasculature phantom (for quality assessment), and experiments with ten 0.5 mm-diameter pencil leads and a leaf skeleton phantom are used for evaluation of the proposed approach. The results show that a location-independent tangential resolution is achieved with 150 spatial sampling and central rotations with angles of ±8°/±16°. With further developments, the proposed detection strategy can replace the conventional detection (rotating a transducer around ROI) in PAT.
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