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Esophageal Perforation-I: Introduction

Esophageal Perforation-I: Introduction

Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....

Esophageal Perforation-II: Clinical Manifestations and Management

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Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:

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Bloodless Laparoscopic Partial Splenectomy Assisted by Bipolar Radiofrequency Excision Hemostatic Device

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Mantle Cell Lymphoma With Non-traumatic Splenic Rupture Requiring Emergency Splenectomy.

Patrick D Plummer¹, Benjamin Yglesias¹, Adam Swiger¹

¹Department of Surgery, Trumbull Regional Medical Center, Warren, USA.

|June 6, 2022

Summary

Mantle cell lymphoma (MCL), a B-cell non-Hodgkin lymphoma (NHL), can present with atraumatic splenic rupture. This case report details a 68-year-old female patient

Keywords:

mantle cell lymphoma non-hodgkin’s lymphomas splenectomy splenic rupture spontaneous rupture

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Area of Science:

Hematology
Oncology
Pathology

Background:

Mantle cell lymphoma (MCL) is a non-Hodgkin lymphoma (NHL) subtype.
MCL exhibits variable clinical behavior, from indolent to aggressive forms.
It predominantly affects males in Western countries, with a median age of diagnosis around 60.

Observation:

A 68-year-old female presented with atraumatic splenic rupture and severe left upper quadrant abdominal pain.
The patient had no prior history of trauma.
An emergency splenectomy was successfully performed, stabilizing the patient.

Findings:

This case highlights an unusual presentation of MCL.
Atraumatic splenic rupture can be a presenting sign of underlying hematologic malignancies.
The report discusses the pathogenesis, clinical presentation, diagnosis, and treatment of MCL and splenic rupture.

Implications:

Increased awareness of rare presentations of MCL is crucial for timely diagnosis.
Splenic rupture, even atraumatic, warrants thorough investigation for underlying conditions.
This case contributes to understanding the diverse clinical manifestations of MCL.