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A rare presentation of multiple sclerosis: Schilder's disease
Reda Taoussi1, Hajar Khattab2, Youssef Sakhy1
1Imaging Department, Ibn Rochd University Hospital, 1 quartier des hôpitaux, Casablanca, Morocco.
Radiology Case Reports
|June 6, 2022
Summary
Schilder's disease, a rare multiple sclerosis variant, affects young adults with atypical symptoms mimicking brain tumors. Early diagnosis and steroid treatment are crucial for better outcomes in this demyelinating condition.
Area of Science:
- Neurology
- Radiology
- Demyelinating Diseases
Background:
- Schilder's disease is a rare variant of multiple sclerosis, primarily affecting adolescents and young adults.
- Clinical presentations can be atypical, often mimicking intracranial neoplasms or abscesses, posing diagnostic challenges.
Observation:
- A 22-year-old patient presented with headache, vomiting, and frontal syndrome.
- Magnetic resonance imaging revealed bilateral demyelinating frontal lesions.
Findings:
- The patient showed a discreet clinical improvement after a corticosteroid bolus.
- However, no significant clinical improvement was observed after 6 months of follow-up.
Implications:
- Schilder's disease, despite being a multiple sclerosis variant, exhibits a monophasic course with potential for severe consequences if treatment is delayed.
- Radiologists and clinicians must be aware of this rare condition for accurate diagnosis and timely management.
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