Related Experiment Video
Updated: Sep 30, 2026

Growing Protein Crystals with Distinct Dimensions Using Automated Crystallization Coupled with In Situ Dynamic Light Scattering
Published on: August 14, 2018
Crystallization in the Winterbottom Shape and Sharp Fluctuation Laws
Manuel Friedrich1, Leonard Kreutz2, Ulisse Stefanelli3,4
1Department of Mathematics, Friedrich-Alexander Universität Erlangen-Nürnberg, Cauerstr. 11, 91058 Erlangen, Germany.
Abstract:
We address finite crystallization in two dimensions in the presence of a flat crystalline substrate. Particles interact through short-range two- and three-body potentials favoring local square-lattice arrangements. An additional interaction term of relative strength couples the particles and the substrate. Our first main result proves crystallization for all , corresponding to the onset of discrete Winterbottom configurations. The proof relies on a stratification technique from [31], characterizing the topology of the bond graph of minimizing configurations. Our second main result concerns fluctuations estimates for . We obtain bounds on the distance between distinct minimizers with the same number N of particles, showing a sharp scaling law when is rational, and when is irrational and algebraic. This reveals a genuine substrate-driven effect on fluctuation laws. As a corollary, we derive a discrete-to-continuum convergence of minimizers towards the Winterbottom equilibrium shape in the large-particle limit.
Related Concept Videos
Crystal Growth: Principles of Crystallization
Initiating crystallization involves manipulating the concentration of the solute and the temperature of the solution. Since crystal growth occurs when the ratio of concentration and solubility of the solute in the solvent – the...
Recrystallization: Solid–Solution Equilibria
Determination of Crystal Structures
X-ray Crystallography
Diffraction
Diffraction is the change in the direction of travel experienced by an electromagnetic wave when it encounters a physical barrier whose dimensions are comparable to those of the wavelength of the light. X-rays are electromagnetic radiation with wavelengths about as long as the distance between neighboring...
Imperfections in Crystal Structure: Point, Line and Plane Defects
Law of Rational Indices

