Did the COVID-19 Pandemic Affect the Management of Patients With Acute Appendicitis?

Deniz Tazeoglu1, Ahmet Cem Esmer1, Bilal Arslan1

  • 1General Surgery, Faculty of Medicine Mersin University, Mersin, TUR.

Cureus
|June 6, 2022
PubMed

Insights

The COVID-19 pandemic delayed acute appendicitis (AA) diagnosis and treatment. While surgical outcomes were unaffected, COVID-19 positivity increased complication risk in patients with severe appendicitis.

Area of Science:

  • Surgery
  • Infectious Diseases
  • Public Health

Background:

  • The COVID-19 pandemic significantly altered global lifestyles and healthcare access.
  • Acute appendicitis (AA) diagnosis and management may have been impacted by pandemic-related changes.

Purpose of the Study:

  • To investigate the effect of the COVID-19 pandemic on the diagnosis and treatment duration of acute appendicitis (AA).
  • To assess the pandemic's impact on AA morbidity and mortality.

Main Methods:

  • Retrospective analysis of AA patients operated on between March 2019 and March 2021, divided into pre-COVID and post-COVID periods.
  • Inclusion criteria: AA diagnosis, appendectomy, complete preoperative data.
  • Comparison of symptom onset to admission time, diagnostic imaging use, surgical techniques, and postoperative outcomes between the two periods.

Main Results:

  • A statistically significant delay in symptom onset to hospital admission was observed in the post-COVID period (p=0.04).
  • Ultrasonography use decreased (p<0.01), while computed tomography use increased (p<0.001) during the pandemic.
  • Laparoscopic appendectomy rates declined (p=0.02), but postoperative complication rates and severity were not significantly different between periods (p=0.24, p=0.68).
  • COVID-19 positivity was associated with a higher risk of postoperative complications (p=0.01).

Conclusions:

  • The COVID-19 pandemic led to delayed diagnosis and treatment for acute appendicitis patients.
  • Pandemic did not significantly affect overall postoperative complication frequency or severity.
  • COVID-19 positivity emerged as a risk factor for complicated appendicitis, including periappendicular abscess, gangrenous, and perforated appendix.

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