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Did the COVID-19 Pandemic Affect the Management of Patients With Acute Appendicitis?
Deniz Tazeoglu1, Ahmet Cem Esmer1, Bilal Arslan1
1General Surgery, Faculty of Medicine Mersin University, Mersin, TUR.
Insights
The COVID-19 pandemic delayed acute appendicitis (AA) diagnosis and treatment. While surgical outcomes were unaffected, COVID-19 positivity increased complication risk in patients with severe appendicitis.
Area of Science:
- Surgery
- Infectious Diseases
- Public Health
Background:
- The COVID-19 pandemic significantly altered global lifestyles and healthcare access.
- Acute appendicitis (AA) diagnosis and management may have been impacted by pandemic-related changes.
Purpose of the Study:
- To investigate the effect of the COVID-19 pandemic on the diagnosis and treatment duration of acute appendicitis (AA).
- To assess the pandemic's impact on AA morbidity and mortality.
Main Methods:
- Retrospective analysis of AA patients operated on between March 2019 and March 2021, divided into pre-COVID and post-COVID periods.
- Inclusion criteria: AA diagnosis, appendectomy, complete preoperative data.
- Comparison of symptom onset to admission time, diagnostic imaging use, surgical techniques, and postoperative outcomes between the two periods.
Main Results:
- A statistically significant delay in symptom onset to hospital admission was observed in the post-COVID period (p=0.04).
- Ultrasonography use decreased (p<0.01), while computed tomography use increased (p<0.001) during the pandemic.
- Laparoscopic appendectomy rates declined (p=0.02), but postoperative complication rates and severity were not significantly different between periods (p=0.24, p=0.68).
- COVID-19 positivity was associated with a higher risk of postoperative complications (p=0.01).
Conclusions:
- The COVID-19 pandemic led to delayed diagnosis and treatment for acute appendicitis patients.
- Pandemic did not significantly affect overall postoperative complication frequency or severity.
- COVID-19 positivity emerged as a risk factor for complicated appendicitis, including periappendicular abscess, gangrenous, and perforated appendix.
Abstract:
Background The coronavirus disease 2019 (COVID-19) pandemic has changed the lives and habits of people all over the world. In this study, it was planned to investigate the effect of the COVID-19 pandemic on the diagnosis and treatment duration of acute appendicitis (AA), morbidity and mortality. Methods The data of patients who were operated on with the diagnosis of AA in our clinic between March 2019 and March 2021, divided into pre-COVID and post-COVID periods, were analyzed. Patients diagnosed with AA, who had the only appendectomy perioperatively, and who had complete preoperative blood analysis and radiological imaging data were included in the study. Results The time from the onset of symptoms to the time of admission to the hospital was statistically significantly longer than in the post-COVID group (p=0.04). During the COVID-19 pandemic period, the use of ultrasonography was statistically significantly reduced (p<0.01); computed tomography use increased (p<0.001). Laparoscopic appendectomy as a surgical technique decreased statistically significantly during the pandemic period (p=0.02). Postoperative complications and the postoperative complication severity degrees were not statistically significant between periods (p=0.24, p=0.68). The risk for the occurrence of postoperative complications in COVID-19 positive patients was statistically higher (p=0.01) (OR: 9.38 95% CI: 1.96 - 44.88). Conclusion The COVID-19 pandemic had caused delays in the admission and diagnosis of patients who might need surgery due to AA. Postoperative complication frequency and complication severity classification were not affected. COVID-19 positivity was a risk factor for complex AA presenting with periappendicular abscess, gangrenous and perforated appendix.
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