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Updated: Sep 20, 2025

Investigation of Synaptic Tagging/Capture and Cross-capture using Acute Hippocampal Slices from Rodents
Published on: September 4, 2015
Synaptic plasticity during systems memory consolidation
1Department of Pharmacology, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan.
Abstract:
After learning, memory is initially encoded in the hippocampus but subsequently stabilized in other brain regions such as the cortex for long-lasting storage. This process is known as systems memory consolidation, and its cellular mechanism has long been a fundamental question. Synaptic plasticity is the major cellular mechanism underlying learning and memory, and is therefore considered a key function in the process of systems memory consolidation. Therefore, many studies have aimed to establish a causal link between synaptic plasticity in the brain and memory-associated behaviors. In this review, I discuss the various lines of research showing the function of synaptic plasticity, mainly in the hippocampus and cortex during memory consolidation.
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