Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Loss of Carboxy Group as CO2: Decarboxylation of β-Ketoacids01:02

Loss of Carboxy Group as CO2: Decarboxylation of β-Ketoacids

3.3K
Carboxylic acids, upon heating, undergo a decarboxylation reaction by releasing carbon dioxide gas. Monocarboxylic acids do not undergo decarboxylation easily. However, a silver salt of carboxylic acid reacts with bromine or iodine under high temperature to release carbon dioxide gas and forms halide with one less carbon. This reaction is called the Hunsdiecker reaction.
3.3K
Reactions of Carboxylic Acids: Introduction01:41

Reactions of Carboxylic Acids: Introduction

3.3K
Carboxylic acids possess an acidic –COOH functional group. The acidity can be attributed to the resonance stabilization of their conjugate base, wherein the negative charge is delocalized over both oxygen atoms.
3.3K
Carboxylic Acid Derivatives: Overview01:15

Carboxylic Acid Derivatives: Overview

4.2K
Carboxylic acid derivatives are formed by replacing the hydroxyl group of carboxylic acids with a different functional group. The most common carboxylic acid derivatives are:
4.2K
Loss of Carboxy Group as CO2: Decarboxylation of Malonic Acid Derivatives01:35

Loss of Carboxy Group as CO2: Decarboxylation of Malonic Acid Derivatives

2.1K
Just like β-keto acids—which upon thermal decarboxylation form ketones—β-dicarboxylic acids undergo decarboxylation to generate monocarboxylic acids with the liberation of carbon dioxide.
2.1K
Preparation of Carboxylic Acids: Carboxylation of Grignard Reagents01:13

Preparation of Carboxylic Acids: Carboxylation of Grignard Reagents

5.0K
Carboxylic acids can be prepared by the carboxylation of Grignard reagents (RMgX). This method is convenient for converting alkyl (primary, secondary or tertiary), vinyl, benzyl, and aryl halides to carboxylic acids with one additional carbon than the starting RMgX.
5.0K
Spectroscopy of Carboxylic Acid Derivatives01:26

Spectroscopy of Carboxylic Acid Derivatives

2.6K
Infrared spectroscopy is primarily used to determine the types of bonds and functional groups. In carboxylic acid derivatives, a typical carbonyl bond absorption is observed around 1650–1850 cm−1. For esters, the absorption is recorded at around 1740 cm−1, while acid halides show the absorption at about 1800 cm−1. Another acid derivative, the acid anhydrides, exhibit two carbonyl absorption around 1760 cm−1 and 1820 cm−1, arising from the symmetrical and...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame journal

Topical Melatonin in Aesthetic Dermatology: From Cutaneous Melatoninergic Biology to Photoprotection, and Skin Rejuvenation.

Clinics in dermatology·2026
Same author

AI in clinical diagnostics in dermatology: applications, validation, and real-world use cases.

Presse medicale (Paris, France : 1983)·2026
Same author

Tanorexia: The psychodermatology of compulsive tanning.

Clinics in dermatology·2026
Same author

Development of a Core Outcome Domain Set for Facial Aging.

JAMA dermatology·2026
Same author

Anti-TNFa As a Treatment Option for Synchronous Folliculitis Keloidalis and Hidradenitis Suppurativa.

International journal of dermatology·2026
Same author

Botulinum Toxin for Lip Inversion in Gummy Smile.

Cureus·2026

Related Experiment Video

Updated: Sep 20, 2025

Apparatus for Harvesting Tissue Microcolumns
06:06

Apparatus for Harvesting Tissue Microcolumns

Published on: October 25, 2018

6.1K

Carboxytherapy in dermatology.

George Kroumpouzos1, Gulhima Arora2, Martin Kassir3

  • 1Department of Dermatology, Alpert Medical School of Brown University, Providence, Rhode Island, USA; GK Dermatology, PC, South Weymouth, Massachusetts, USA.

Clinics in Dermatology
|June 6, 2022
PubMed
Summary

Carboxytherapy, injecting carbon dioxide into tissues, offers aesthetic benefits for skin rejuvenation, scars, and cellulite. However, potential drawbacks like emphysema and suboptimal results require careful consideration.

More Related Videos

Cytotoxic Efficacy of Photodynamic Therapy in Osteosarcoma Cells In Vitro
08:04

Cytotoxic Efficacy of Photodynamic Therapy in Osteosarcoma Cells In Vitro

Published on: March 18, 2014

12.9K
Encapsulation of Cancer Therapeutic Agent Dacarbazine Using Nanostructured Lipid Carrier
07:53

Encapsulation of Cancer Therapeutic Agent Dacarbazine Using Nanostructured Lipid Carrier

Published on: April 26, 2016

11.2K

Related Experiment Videos

Last Updated: Sep 20, 2025

Apparatus for Harvesting Tissue Microcolumns
06:06

Apparatus for Harvesting Tissue Microcolumns

Published on: October 25, 2018

6.1K
Cytotoxic Efficacy of Photodynamic Therapy in Osteosarcoma Cells In Vitro
08:04

Cytotoxic Efficacy of Photodynamic Therapy in Osteosarcoma Cells In Vitro

Published on: March 18, 2014

12.9K
Encapsulation of Cancer Therapeutic Agent Dacarbazine Using Nanostructured Lipid Carrier
07:53

Encapsulation of Cancer Therapeutic Agent Dacarbazine Using Nanostructured Lipid Carrier

Published on: April 26, 2016

11.2K

Area of Science:

  • Dermatology
  • Aesthetic Medicine

Background:

  • Carboxytherapy involves injecting sterile carbon dioxide gas into subdermal tissue.
  • Its application has expanded for managing various medical and aesthetic conditions.

Purpose of the Study:

  • To evaluate the efficacy and applications of carboxytherapy in dermatologic treatments.
  • To review existing literature on carboxytherapy's use in aesthetic and reconstructive dermatology.

Main Methods:

  • Systematic review of English-language articles published through January 2021.
  • Searches conducted on electronic databases including MEDLINE and PubMed.

Main Results:

  • Carboxytherapy shows promise for skin rejuvenation, atrophic scars, striae distensae (stretch marks), cellulite, and alopecia.
  • The procedure is an attractive option for various dermatologic concerns.

Conclusions:

  • Carboxytherapy presents a viable aesthetic option for multiple dermatologic conditions.
  • Potential adverse effects include inadvertent lipolysis, persistent emphysema, and unsatisfactory outcomes.