[Characteristics of development of the rat embryonal lung after resection of the maternal lung]

Histological and electron microscopic studies of embryos from pulmonectomized female rats have revealed retarded differentiation of respiratory rudiment epithelium manifested in delayed appearance of osmiophylic laminar corpuscles and decreased number of type II pneumocytes in respiratory rudiment lining. Osmiophylic laminar corpuscles in them were less differentiated, as compared to the control. In addition, embryonic lungs in pulmonectomized rats were characterized by excessive mesenchyma development and respective decrease in respiratory rudiment area. It is concluded that embryonic lungs developed during pulmonary tissue deficit in the mother are functionally less mature.