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Accuracy of quality of life questionnaire as a diagnostic tool for SARS-CoV-2 pulmonary sequelae
Luca Vannini1, Ana Laynez-Carnicero2, Carlos Bobis-Alvarez2
1Department of Cardiology, Hospital Nuestra Señora de Candelaria, Tenerife, Spain; Department of Preventive Medicine and Public Health University Rey Juan Carlos, Madrid, Spain.
Background:
Follow-up after hospital discharge of SARS-CoV-2 survivors represents a huge burden on the healthcare system. We attempt to assess the utility of symptoms and health-related quality of life questionnaire (SF-12) to identify SARS CoV2 pulmonary sequelae.
Methods:
Prospective, non-interventional follow-up study. A cardiopulmonary exercise test, functional respiratory test (PFT), SF12 questionnaire were performed after hospitalization at six months after the first positive PCR smear.
Results:
41 patients were included, female (39%), mean age 57.3±13.7 years. 70% persisted with symptoms. 46% presented a maximum oxygen consumption below 80% of predicted. SF-12 physical domain score was significantly reduced in patients with altered PFT (32.7 vs. 45.9; p<0.001) and obtained the best sensitivity and specificity to identify PFT alterations (AUC 0.862, Sensitivity 85.7%, Specificity 81.5%).
Conclusions:
SF-12 questionnaire shows high sensitivity and specificity to detect SARS CoV2 survivors with pulmonary function alterations.
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