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Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases

Longitudinal In Vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases

Published on: December 6, 2016

Neuroimaging in small vessel disease.

L Mena Romo¹, M Gómez-Choco¹

¹Complex Hospitalari Despí Moisès Broggi, Servicio de Neurología, Spain.

Hipertension Y Riesgo Vascular

|June 8, 2022

Summary

This review explores neuroimaging in small vessel disease, a common vascular pathology affecting cerebral blood vessels and the blood-brain barrier. Magnetic resonance imaging reveals key signs like white matter hyperintensities and microbleeds.

Keywords:

Brain microbleeds CMB Cerebral small vessel disease Lesiones de sustancia blanca Microsangrados cerebrales SVD WMH White matter hyperintensity

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Area of Science:

Neurology
Radiology
Vascular Biology

Background:

Small vessel disease is the most prevalent vascular pathology.
It originates from the affliction of small cerebral vessels, leading to blood-brain barrier disruption.
Clinical implications are significant.

Purpose of the Study:

To conduct a literature review on neuroimaging in small vessel disease.
To summarize current understanding and identify key neuroimaging findings.

Main Methods:

Literature search via Pubmed using terms: cerebral small vessel disease, white matter hyperintensity, brain microbleed, WBC.
No year filter was applied to the search.

Main Results:

Magnetic resonance imaging identifies various disease manifestations: white matter hyperintensities, microbleeds, and lacunar infarcts.
Emerging techniques like brain blood flow measurements enhance understanding of disease pathophysiology.

Conclusions:

Neuroimaging plays a crucial role in diagnosing and understanding small vessel disease.
Advanced imaging techniques are vital for further elucidating the pathophysiology and clinical impact.