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Rational Design of P450 aMOx for Improving Anti-Markovnikov Selectivity Based on the "Butterfly" Model

Yue Pan1, Jinxiao Bao1, Xingyi Zhang2

  • 1Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, Shanghai Key Laboratory of Green Chemistry and Chemical Process, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, China.

Frontiers in Molecular Biosciences
|June 9, 2022
PubMed

Keywords:
anti-Markovnikov (AM) oxidationexperimental alanine scanmolecular dynamic simulationsproduct selectivityrational design“butterfly” model

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