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Pain after Interventional Radiology in Oncology: A Case-Control Study from a 5-Year Cohort.
Narimane Ayaden1, Philippe Sitbon1, Arnaud Pages2
1Gustave Roussy, Service d'Anesthésie, F-94805 Villejuif, France.
Post-procedural pain after interventional radiology in oncology is common, particularly for women and younger patients. Intraoperative ketoprofen and limiting remifentanil doses can reduce severe pain.
Area of Science:
- Oncology
- Interventional Radiology
- Pain Management
Background:
- Interventional radiology is crucial for cancer treatment, yet post-procedural pain is underreported.
- Understanding pain factors is vital for improving patient care in oncology.
Purpose of the Study:
- To quantify postoperative pain following interventional radiology procedures in cancer patients.
- To identify key pre- and intraoperative factors associated with this pain.
Main Methods:
- Retrospective cohort study of 4411 interventional radiology procedures (2015-2019).
- Standardized anesthetic protocols based on procedure type.
- Case-control study comparing severe pain patients with pain-free controls.
Main Results:
- Severe pain in the post-anesthesia care unit (PACU) was more frequent in women and younger patients, and after general anesthesia.
- Procedures like arterial embolization and longer intervention times (>160 min) correlated with higher pain.
- High-dose remifentanil was a risk factor; intraoperative ketoprofen reduced severe pain incidence.
Conclusions:
- Post-interventional radiology pain severity is influenced by procedure type/duration, anesthesia, and prior opiate use.
- Optimizing remifentanil dosage and using intraoperative analgesics like ketoprofen may mitigate severe post-procedural pain.
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