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Updated: Sep 20, 2025

Intra-Operative Neural Monitoring of Thyroid Surgery in a Porcine Model
Published on: February 11, 2019
Optimal Monitoring Technology for Pediatric Thyroidectomy
Daqi Zhang1, Hui Sun1, Hoon Yub Kim2
1Division of Thyroid Surgery, China-Japan Union Hospital of Jilin University, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Changchun 130033, China.
Insights
Intraoperative neural monitoring in pediatric thyroid surgery showed a low rate of transient recurrent laryngeal nerve injuries. This study highlights the safety and effectiveness of these techniques in young patients.
Area of Science:
- Pediatric Surgery
- Otolaryngology
- Neurosurgery
Background:
- Intraoperative neural monitoring (INM) is crucial for preserving nerve function during thyroid surgery.
- Data on INM in pediatric populations is limited, necessitating further investigation.
Purpose of the Study:
- To characterize INM use and outcomes in pediatric patients undergoing thyroid surgery.
- To determine the rate of recurrent laryngeal nerve (RLN) complications in this demographic.
Main Methods:
- Retrospective analysis of 37 pediatric patients (<18 years) undergoing open thyroid surgery between 2015-2021.
- Inclusion of various thyroidectomy types (total, lobectomy) and lymph node dissections.
- Assessment of electromyographic profiles and RLN complication rates.
Main Results:
- No significant difference in electromyographic profiles between different monitoring devices.
- Five out of 61 (8.2%) at-risk nerves experienced transient RLN injury with signal loss.
- All injuries resolved within 4 months, indicating temporary nerve dysfunction.
Conclusions:
- INM is feasible and safe in pediatric thyroid surgery, with a low incidence of transient RLN injuries.
- Both adhesive and embedded endotracheal tubes are effective; more invasive methods may be needed for very young children.
- This study represents the first report on INM management in Italian pediatric patients.
Abstract:
This retrospective study aimed to describe, firstly, characteristics and outcomes of the intraoperative neural monitoring technology in the pediatric population, and secondarily the recurrent laryngeal nerve complication rate. Thirty-seven patients (age <18 years) operated on from 2015 to 2021 by conventional open thyroid surgery were included. Twenty-four (64.9%) total thyroidectomies and 13 (35.1%) lobectomies were performed. Seven central and six lateral lymph node dissections completed 13 bilateral procedures. Histology showed malignancy in 45.9% of the cases. The differences between the electromyographic profiles of endotracheal tubes or electrodes for continuous monitoring were not statistically significant. In our series of young patients, both adhesive (even in 4- or 5-year-olds) and embedded endotracheal tubes were used, while in patients 3 years old or younger, the use of a more invasive detection method with transcartilage placement recording electrodes was required. Overall, out of 61 total at-risk nerves, 5 (8.2%) recurrent laryngeal nerves were injured with consequent intraoperative loss of the signal; however, all these lesions were transient, restoring their normal functionality within 4 months from surgical procedure. To our knowledge, this is the first study of intraoperative neural monitoring management in a cohort of Italian pediatric patients.
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