Related Experiment Video
Updated: Sep 20, 2025

09:49
Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
Published on: December 28, 2021
3.5K
Simultaneous Separation and Tumescence: A New Paradigm for Liposuction Donor Site Preparation
Daniel Del Vecchio1, Simeon Wall2, Michael J Stein3
1Department of Plastic Surgery, Massachusetts General Hospital, Boston, MA, USA.
Aesthetic Surgery Journal
|June 11, 2022
Summary
Simultaneous separation and tumescence (SST) enhances liposuction safety and efficiency. This new technique improves vasoconstriction compared to traditional methods, potentially allowing for larger fat extraction volumes.
Area of Science:
- Plastic Surgery
- Surgical Innovation
Background:
- Liposuction and fat transplantation are increasingly popular in the US due to their safety and effectiveness.
- Technical advancements like tumescent infiltration and fat separation improve outcomes but increase procedure time.
- Simultaneous separation and tumescence (SST) is a novel technique merging these innovations for enhanced liposuction safety and efficiency.
Purpose of the Study:
- To describe the authors' technique for Simultaneous separation and tumescence (SST) in over 1200 patients across 6 years.
- To compare the vasoconstrictive effectiveness of SST with traditional Klein infiltration techniques using a split abdomen study design.
Main Methods:
- A split abdomen study was conducted comparing SST with traditional Klein infiltration.
- Quantification perfusion analysis using indocyanine green angiography was performed on 4 patients.
- Mean relative vasoconstriction scores were calculated for each technique relative to the umbilicus.
Main Results:
- Simultaneous separation and tumescence (SST) demonstrated significantly higher vasoconstriction compared to Klein infiltration (89.6% vs 48.1% at 2 minutes, P < 0.0001).
- SST exhibited a similar complication rate and utilized comparable infiltrative volumes to traditional Klein tumescence techniques.
Conclusions:
- Simultaneous separation and tumescence (SST) offers a significant advancement over the traditional Klein tumescence method for liposuction.
- SST is expected to lead to more efficient surgical times and potentially enable safer extraction of larger fat volumes.

