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Predictors of mortality in COVID-19 induced acute kidney injury
Enver Yüksel1, Songül Arac2, Derya Deniz Altintaş3
1Department of Nephrology, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey.
Background:
We aimed to investigate the predictors of mortality in patients with COVID-19-induced acute kidney injury (COV-AKI).
Methods:
We enrolled 803 patients who developed COV-AKI. The patients were divided into two groups: survivors and nonsurvivors.
Results:
A multivariate logistic regression analysis showed that age (p < 0.001), increased admission C-reactive protein (p = 0.016), procalcitonin (p = 0.019), creatine kinase (p = 0.04), KDIGO stage 1 versus 2 AKI (p < 0.001), KDIGO stage 1 versus 3 (p < 0.001), the need for renal replacement therapy (p = 0.002) and highest creatinine (p = 0.004) were significantly associated with increased inhospital mortality. However, the mortality of patients with AKI on admission (p = 0.002) was found to be lower than those who developed AKI after hospitalization.
Conclusions:
Among patients with COV-AKI, high-inflammatory response and severe AKI were associated with significantly higher mortality.
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