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Outcomes from a tertiary care center using a catheter thrombectomy system for managing acute iliofemoral deep vein

Michael A Jolly1, Marie M Lockhart2, Deep Shah3

  • 1Interventional Cardiology and Vascular Medicine, Riverside Methodist Hospital, OhioHealth Heart and Vascular, Columbus, OH.

Journal of Vascular Surgery. Venous and Lymphatic Disorders
|June 12, 2022
PubMed

Insights

The ClotTriever system effectively removed acute iliofemoral deep vein thrombosis (DVT) in 97% of patients. This thrombectomy approach demonstrated safety and efficacy, even for patients with contraindications to thrombolysis.

Area of Science:

  • Vascular Surgery
  • Interventional Radiology
  • Cardiovascular Medicine

Background:

  • Acute iliofemoral deep vein thrombosis (IF-DVT) presents treatment challenges, particularly regarding complete thrombus removal and bleeding risks associated with thrombolysis.
  • Existing endovascular devices often struggle with complete clot clearance, necessitating adjunctive therapies like thrombolysis.

Purpose of the Study:

  • To evaluate the safety and efficacy of the ClotTriever thrombectomy system in a large, single-center cohort of patients with acute IF-DVT.
  • To assess the system's performance in patients with contraindications to thrombolytic therapy.

Main Methods:

  • A retrospective review of 96 consecutive patients with acute IF-DVT treated with the ClotTriever system.
  • Efficacy assessed by independent core imaging laboratory; safety evaluated during index hospitalization.
  • Vein patency assessed via duplex ultrasound at 30 days post-procedure.

Main Results:

  • 97% of patients achieved ≥75% thrombus removal.
  • No mortality, major bleeding, or device-related complications were reported.
  • At 30 days, 97% of assessed patients showed normal flow and 83% normal compressibility.

Conclusions:

  • The ClotTriever thrombectomy catheter is a safe and effective treatment option for acute IF-DVT.
  • The system offers a viable alternative for patients unsuitable for thrombolytic therapy.
  • Real-world data supports the use of ClotTriever in managing acute iliofemoral deep vein thrombosis.
Abstract

Keywords:
BleedingDeep vein thrombosisIliofemoralThrombectomyThrombolysis

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