Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Irbesartan ameliorates high‑glucose‑induced epithelial‑mesenchymal transition by downregulating the expression of NLRP3 in HK‑2 cells.

Molecular medicine reports·2026
Same author

Tracer Techniques in Ophthalmology: Ocular Applications and Systemic Connections.

Diagnostics (Basel, Switzerland)·2026
Same author

The Visual Function of Emergent Transnasal Endoscopic Orbital Decompression Surgery for Patients With Steroid-Resistant Dysthyroid Optic Neuropathy.

The Journal of craniofacial surgery·2026
Same author

Summary of the best evidence for adult nasal high-flow oxygen therapy nebulization management.

Frontiers in medicine·2026
Same author

Knowledge, attitudes, and practices of ICU nurses regarding daily sedation interruption: a cross-sectional study.

Frontiers in medicine·2026
Same author

Examining the status quo and related factors of clinical nurses' spare-time planning.

Frontiers in public health·2026
Same journal

Evaluation of an open-face 8-channel transmit 64-channel receive 7T head coil for neuroimaging.

Frontiers in neuroscience·2026
Same journal

Acoustic stimulation in pain management: neurobiological mechanisms and clinical applications-a narrative review.

Frontiers in neuroscience·2026
Same journal

Local brain connectome parameters across the spectrum of clinical cognitive decline.

Frontiers in neuroscience·2026
Same journal

Body mass index affects EEG microstate dynamics through blood viscosity in high-altitude environments.

Frontiers in neuroscience·2026
Same journal

Disrupted glymphatic function and its relationship with sleep and cognitive impairment in ME/CFS assessed via DTI-ALPS.

Frontiers in neuroscience·2026
Same journal

Neuromorphic-inspired multi-view global-local fusion for IR-UWB radar dynamic gesture recognition.

Frontiers in neuroscience·2026
See all related articles

Related Experiment Video

Updated: Sep 8, 2025

Qualitative and Comparative Cortical Activity Data Analyses from a Functional Near-Infrared Spectroscopy Experiment Applying Block Design
06:18

Qualitative and Comparative Cortical Activity Data Analyses from a Functional Near-Infrared Spectroscopy Experiment Applying Block Design

Published on: December 3, 2020

3.8K

A Decrease in Hemodynamic Response in the Right Postcentral Cortex Is Associated With Treatment-Resistant Auditory

Nana Liang1, Sha Liu1,2, Xinrong Li1,2

  • 1Department of Psychiatry, First Hospital/First Clinical Medical College of Shanxi Medical University, Taiyuan, China.

Frontiers in Neuroscience
|June 13, 2022
PubMed
Summary
This summary is machine-generated.

Treatment-resistant auditory verbal hallucinations (TRAVHs) in schizophrenia (SCZ) are linked to altered brain activity in prefrontal-temporal regions. This fNIRS study reveals specific hemodynamic differences in patients with TRAVH, suggesting potential targets for early intervention.

Keywords:
auditory verbal hallucinationshemodynamic responsenear-infrared spectroscopyschizophreniatreatment-resistantverbal fluency task

More Related Videos

Author Spotlight: Advancing Upper Limb Rehabilitation in Patients with Right Hemisphere Damage Using Assisted Active Exercise
04:43

Author Spotlight: Advancing Upper Limb Rehabilitation in Patients with Right Hemisphere Damage Using Assisted Active Exercise

Published on: February 9, 2024

1.2K
Simultaneous Data Collection of fMRI and fNIRS Measurements Using a Whole-Head Optode Array and Short-Distance Channels
08:19

Simultaneous Data Collection of fMRI and fNIRS Measurements Using a Whole-Head Optode Array and Short-Distance Channels

Published on: October 20, 2023

1.2K

Related Experiment Videos

Last Updated: Sep 8, 2025

Qualitative and Comparative Cortical Activity Data Analyses from a Functional Near-Infrared Spectroscopy Experiment Applying Block Design
06:18

Qualitative and Comparative Cortical Activity Data Analyses from a Functional Near-Infrared Spectroscopy Experiment Applying Block Design

Published on: December 3, 2020

3.8K
Author Spotlight: Advancing Upper Limb Rehabilitation in Patients with Right Hemisphere Damage Using Assisted Active Exercise
04:43

Author Spotlight: Advancing Upper Limb Rehabilitation in Patients with Right Hemisphere Damage Using Assisted Active Exercise

Published on: February 9, 2024

1.2K
Simultaneous Data Collection of fMRI and fNIRS Measurements Using a Whole-Head Optode Array and Short-Distance Channels
08:19

Simultaneous Data Collection of fMRI and fNIRS Measurements Using a Whole-Head Optode Array and Short-Distance Channels

Published on: October 20, 2023

1.2K

Area of Science:

  • Neuroscience
  • Psychiatry
  • Medical Imaging

Background:

  • Treatment-resistant auditory verbal hallucinations (TRAVHs) in schizophrenia (SCZ) increase risks of violence, suicide, and hospitalization.
  • Limited research exists on the specific functional brain activity correlating with TRAVH.
  • Functional near-infrared spectroscopy (fNIRS) offers a portable method to study brain activation during tasks.

Purpose of the Study:

  • To investigate differences in cerebral hemodynamic function among patients with SCZ-TRAVH, SCZ without AVH (SCZ-nAVH), and healthy controls (HCs).
  • To identify neural abnormalities specifically associated with TRAVH using fNIRS during a verbal fluency task (VFT).

Main Methods:

  • A 52-channel fNIRS system monitored hemodynamic changes in SCZ-TRAVH (n=38), SCZ-nAVH (n=35), and HC (n=30) during a VFT.
  • MATLAB was used to analyze fNIRS data, calculating Δβ (change in oxygenated hemoglobin) to represent brain cortical activity response.
  • VFT performance, clinical history, and symptom severity were recorded.

Main Results:

  • Significant differences in Δβ values were observed across 26 channels in prefrontal-temporal cortical regions among the three groups (p < 0.043).
  • Patients with schizophrenia (SCZ-TRAVH and SCZ-nAVH) showed significantly lower Δβ values than HCs in 24 channels (p < 0.026).
  • Abnormal activation in the right postcentral gyrus (ch22) correlated with TRAVH severity.

Conclusions:

  • Specific prefrontal cortex regions are implicated in TRAVH.
  • These findings may inform early intervention strategies for psychosis.