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Updated: Sep 8, 2025

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World
Published on: April 7, 2020
Regular Late Bedtime Significantly Affects the Skin Physiological Characteristics and Skin Bacterial Microbiome
Li Shao1, Sujing Jiang1, Yan Li2
1School of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai, People's Republic of China.
Regular late bedtime negatively impacts skin health by impairing the skin barrier and altering facial bacterial microbiome diversity. This unhealthy sleep pattern reduces skin hydration and elasticity while increasing wrinkles and sebum.
Area of Science:
- Dermatology
- Microbiology
- Sleep Science
Background:
- Late bedtime is a prevalent unhealthy sleep pattern affecting overall health and circadian rhythm.
- Its specific impact on skin characteristics, especially the skin microbiome, remains under-researched.
Purpose of the Study:
- To investigate the effects of regular late bedtime on skin physiological parameters.
- To analyze changes in the facial bacterial microbiome associated with late bedtime.
Main Methods:
- 219 Chinese women (aged 18-38) in Shanghai were categorized into early (S0) and late (S1) bedtime groups.
- Facial skin parameters were measured non-invasively; skin microbiome was analyzed using 16S rRNA high-throughput sequencing.
Main Results:
- Late bedtime significantly decreased skin hydration, firmness, and elasticity, while increasing TEWL, sebum, and wrinkles.
- Facial bacterial diversity (α-diversity, Sobs, Ace, Chao) decreased, with increased Pseudomonas and decreased beneficial bacteria.
- Significant correlations were found between specific bacterial abundances and skin physiological parameters.
Conclusions:
- Bedtime is crucial for maintaining skin health.
- Regular late bedtime damages the skin barrier and structure.
- It also reduces the diversity and alters the composition of the facial bacterial microbiome.
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